A study of the sensitivity of biomechanical models of the spine for scoliosis brace design

Koutras, Christos; Pérez, Jesús; Kardash, Kateryna; Otaduy, Miguel Á.

doi:10.1016/j.cmpb.2021.106125

Cited by 10 publications

(10 citation statements)

References 49 publications

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“…The use of a biomechanical model of the torso as regularizer suggests the question of what degree of biomechanical accuracy is required. We choose a multibody model of the torso skeleton, with bones modeled as rigid bodies, joints modeled as compliant 6D joints, and a homogeneous finite-element model of soft tissue coupled to the bones ( Koutras et al, 2021 ). We model bones as rigid bodies because this assumption is on par with the degrees of freedom we wish to estimate, i.e., the bone transformations of a template model.…”

Section: Methods/morphing Algorithmmentioning

confidence: 99%

“…The deformation cost function is nothing else but the elastic energy of the biomechanical model, which depends on the complete set of DoFs, E deformation ( x ). We refer to ( Koutras et al, 2021 ) for full details on the parameterization and computation of the elastic energy of the biomechanical model.…”

Section: Methods/morphing Algorithmmentioning

confidence: 99%

“… Dicko et al (2015) developed a hybrid lumbar spine model containing rigid bodies, FEM and contact mechanics. Koutras et al (2021) developed a comprehensive model of the torso, including the spine, the rib cage, and soft tissue.…”

Section: Introductionmentioning

confidence: 99%

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Biomechanical Morphing for Personalized Fitting of Scoliotic Torso Skeleton Models

Koutras

Shayestehpour

Pérez

et al. 2022

Front. Bioeng. Biotechnol.

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The use of patient-specific biomechanical models offers many opportunities in the treatment of adolescent idiopathic scoliosis, such as the design of personalized braces. The first step in the development of these patient-specific models is to fit the geometry of the torso skeleton to the patient’s anatomy. However, existing methods rely on high-quality imaging data. The exposure to radiation of these methods limits their applicability for regular monitoring of patients. We present a method to fit personalized models of the torso skeleton that takes as input biplanar low-dose radiographs. The method morphs a template to fit annotated points on visible portions of the spine, and it relies on a default biomechanical model of the torso for regularization and robust fitting of hardly visible parts of the torso skeleton, such as the rib cage. The proposed method provides an accurate and robust solution to obtain personalized models of the torso skeleton, which can be adopted as part of regular management of scoliosis patients. We have evaluated the method on ten young patients who participated in our study. We have analyzed and compared clinical metrics on the spine and the full torso skeleton, and we have found that the accuracy of the method is at least comparable to other methods that require more demanding imaging methods, while it offers superior robustness to artifacts such as interpenetration of ribs. Normal-dose X-rays were available for one of the patients, and for the other nine we acquired low-dose X-rays, allowing us to validate that the accuracy of the method persisted under less invasive imaging modalities.

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Section: Methods/morphing Algorithmmentioning

confidence: 99%

Section: Methods/morphing Algorithmmentioning

confidence: 99%

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Biomechanical Morphing for Personalized Fitting of Scoliotic Torso Skeleton Models

Koutras

Shayestehpour

Pérez

et al. 2022

Front. Bioeng. Biotechnol.

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“…We put the focus on modeling biomechanics elements that affect the deformation of the thoracolumbar spine under forces produced by a scoliosis brace. To this end, we largely rely on previous work for the development of the trunk model ( Koutras et al, 2021 ) and personalization of its geometry ( Koutras et al, 2022 ) (mechanical personalization is left as future work).…”

Section: Introductionmentioning

confidence: 99%

Design of personalized scoliosis braces based on differentiable biomechanics—Synthetic study

Kardash

Koutras

Otaduy

2022

Front. Bioeng. Biotechnol.

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This work describes a computational methodology for the design of braces for adolescent idiopathic scoliosis. The proposed methodology relies on a personalized simulation model of the patient’s trunk, and automatically searches for the brace geometry that optimizes the trade-off between clinical improvement and patient comfort. To do this, we introduce a formulation of differentiable biomechanics of the patient’s trunk, the brace, and their interaction. We design a simulation model that is differentiable with respect to both the deformation state and the brace design parameters, and we show how this differentiable model is used for the efficient update of brace design parameters within a numerical optimization algorithm. To evaluate the proposed methodology, we have obtained trunk models with personalized geometry for five patients of adolescent idiopathic scoliosis, and we have designed Boston-type braces. In a simulation setting, the designed braces improve clinical metrics by 45% on average, under acceptable comfort conditions. In the future, the methodology can be extended beyond synthetic validation, and tested with physical braces on the actual patients.

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“…The sensitivity and importance of the biomechanical vibration models have been recently focused on because of their importance in designing the seats of different modes of transport at a low cost and with high accuracy. Koutras et al (2021) developed a comprehensive biomechanical vibration model of the torso, including soft tissue, ribcage and spine under typical loading conditions of scoliosis braces.…”

Section: Introductionmentioning

confidence: 99%

Analytical and Numerical Investigations of Mechanical Vibration in the Vertical Direction of a Human Body in a Driving Vehicle using Biomechanical Vibration Model

Al-Baghdadi¹,

Jweeg²,

Al-Waily³

2021

JST

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The main reason that affects the discomfort in a driving vehicle is the vibration response. The human body vibration leads to many malfunctions in both comfort and performance in human health. As a result, the human body’s simulation in sitting posture in the driving vehicle has a strategic relationship for all Tires and vehicles manufacturers. The digital process simulation of the human body seat vehicle vibration shows two significant advantages. The first advantage is the prevention of the high-cost modifications in the construction stage of the vehicle, while the second one describes the stability test during the undesirable vibrations. This study modelled the human body’s dynamic characterisations, natural frequency, and mechanical response when seated in the driving vehicle with vibration transmissibility in the vertical direction have been using the biomechanical vibration model. The vertical vibrations and the transmissibility of the human body dynamic response are presented in detail. Exciting results have been obtained, and they are significant for human health, which relates to sitting posture in the driving vehicle. It can assist in understanding the influences of low-frequency vibration on human health, comfort, and performance, and therefore it could be applied for ride comfort evaluation. An analytical solution to derive the general equations of motion for the human system was developed. Then, using the vibration analysis technique and the corresponding equations, the accurate dynamic response of the selected mode is identified. Furthermore, the mathematical modelling for free vibration using the finite element analysis has been performed to determine the appropriate values and set its description. Then, the comparison results of the two techniques have been carried out.

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A study of the sensitivity of biomechanical models of the spine for scoliosis brace design

Cited by 10 publications

References 49 publications

Biomechanical Morphing for Personalized Fitting of Scoliotic Torso Skeleton Models

Biomechanical Morphing for Personalized Fitting of Scoliotic Torso Skeleton Models

Design of personalized scoliosis braces based on differentiable biomechanics—Synthetic study

Analytical and Numerical Investigations of Mechanical Vibration in the Vertical Direction of a Human Body in a Driving Vehicle using Biomechanical Vibration Model

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