1990
DOI: 10.1097/00006534-199012000-00019
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A Study of the Relationship Between Blood Flow and Bacterial Inoculation in Musculocutaneous and Fasciocutaneous Flaps

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Cited by 187 publications
(88 citation statements)
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“…This maneuver is not without its own attendant morbidity, including the potential of a significant cosmetic deformity. A free flap might then be preferable, especially to gain the immunological advantages of muscle (13), but a single muscle also might not be large enough (9).…”
Section: Discussionmentioning
confidence: 99%
“…This maneuver is not without its own attendant morbidity, including the potential of a significant cosmetic deformity. A free flap might then be preferable, especially to gain the immunological advantages of muscle (13), but a single muscle also might not be large enough (9).…”
Section: Discussionmentioning
confidence: 99%
“…Despite a higher vascular density in fasciocutaneous flaps, muscle flaps display a more rapid rate of wound and fracture healing and also have increased antimicrobial properties according to various reports. 9,10,27,28 Muscle flaps have also been shown to promote bone repair secondary to a greater amount of osteogenic mesenchymal stem cells and bone anabolics such as interleukin-6 and fibroblast grow factor-2. 29,30 Multiple animal studies have demonstrated the importance of muscle coverage on fracture sites, although tissue transfer has not been directly examined within these studies.…”
Section: Translational Relevancementioning
confidence: 99%
“…Muscle flaps also have demonstrated more rapid collagen deposition and greater tissue ingrowth. [1][2][3] These advantageous characteristics likely account for their high level of success when used to manage hostile wounds. Regardless of their ability to inhibit bacterial growth, muscle flaps should not be used in an inadequately prepared wound bed.…”
Section: Versatilitymentioning
confidence: 99%