A study of the period of isovolumic relaxation in normal subjects and in patients with heart disease

Benchimol, Alberto; Ellis, Joseph G.

doi:10.1016/0002-9149(67)90533-4

Cited by 70 publications

(20 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…", [24][25][26][27] Although the normal values for systolic time intervals using echographic techniques are not available from previous publications, the values obtained in this study were in the previously described normal range obtained by using the apexcardiogram, phonocardiogram, and carotid pulse tracing.1' 24,26,28 The isometric contraction period obtained in this study by the time-motion curve of the posterior wall echogram demonstrated significant differences between patients with acute myocardial infarction and Circulation, Volume XLIII, June 1971 those without. This finding further supports a reduction in myocardial contractility in patients with acute myocardial infarction as predicted by measurements of posterior wall excursion and mean velocity and provides another bedside means for assessing myocardial contractility in patients without a detectable apical impulse.…”

Section: Comparison Of Measurement Datasupporting

confidence: 53%

Ultrasonic Measurement of Left Ventricular Wall Motion in Acute Myocardial Infarction

et al. 1971

View full text Add to dashboard Cite

The time-motion representation of the echogram was used to evaluate the left ventricular posterior wall motion in myocardial infarction. The left ventricular posterior wall echo was obtained in 10 normal subjects and 26 patients with chest pain admitted to a coronary care unit, including 11 with acute myocardial infarction (group 1), nine with old myocardial infarction (group 2), and six with chest pain of miscellaneous origin (group 3). The total amplitude of posterior wall excursion, left ventricular isometric contraction time, left ventricular systolic ejection time, and mean posterior wall velocity (ratio of posterior wall excursion to ejection time) were measured. By using the measurements of posterior wall excursion, mean posterior wall velocity, and isometric contraction time, group 1 patients were differentiated from those of groups 2 and 3 and from the normal subjects (all P < 0.01). The data from patients in groups 2 and 3 were not statistically different from those of normal subjects. The measurements obtained by the time-motion curve of the left ventricular posterior wall echo appear to be of value in the bedside evaluation of acute myocardial infarction.

show abstract

Section: Comparison Of Measurement Datasupporting

confidence: 53%

Ultrasonic Measurement of Left Ventricular Wall Motion in Acute Myocardial Infarction

et al. 1971

View full text Add to dashboard Cite

show abstract

“…However, Mancini et al [1] in their original study, showed that the IVI was to a large extent independent of age. The same observation has also been made for systolic time intervals [5]. The level of the load, estimated by the duration of exercise, was also significantly lower in the CAD group.…”

Section: Discussionsupporting

confidence: 72%

Left Ventricular Functional Recovery from Exercise in Normals and Patients with Coronary Heart Disease

1987

View full text Add to dashboard Cite

Little information is available regarding left ventricular (LV) functional recovery from treadmill exercise. Accordingly, we used a recently described ultrasound index of LV function, the isovolumic index (IVI), to assess LV performance before and after exercise in 9 normal middle-aged men and 12 male patients with coronary artery disease (CAD). The IVI was measured at rest and at each minute for at least 10 min after completion of the Bruce protocol; normals had maximal tests and CAD patients had symptom limited studies. At rest the IVI value for normals was 26.2 ± 2.1 (SD) and it was 43.5 ± 8.2 for CAD patients (p < 0.001); isovolumic times were longer in CAD patients (137 ± 26 vs. 89 ± 8 ms, p < 0.001). The rate of recovery from exercise did not differ between normals and CAD patients. We conclude that despite depression of resting LV performance in CAD patients, the time course of functional recovery of the left ventricle from exercise is not different from normal subjects.

show abstract

“…Alterations in LV relaxation have been shown to be an early manifestation of cardiac impairment often preceding abnormalities in ventricular systolic function (4,15,21,27). A slowed relaxation rate might result in incomplete relaxation and thereby in reduced early diastolic filling.…”

Section: Discussionmentioning

confidence: 99%

Left Ventricular Systolic and Diastolic Function during Coronary Arteriography before and after Acute Left Ventricular Failure in Dogs

Kløw¹,

Mortensen²,

Refsum³

1991

Acta Radiol

View full text Add to dashboard Cite

A study of the period of isovolumic relaxation in normal subjects and in patients with heart disease

Cited by 70 publications

References 33 publications

Ultrasonic Measurement of Left Ventricular Wall Motion in Acute Myocardial Infarction

Ultrasonic Measurement of Left Ventricular Wall Motion in Acute Myocardial Infarction

Left Ventricular Functional Recovery from Exercise in Normals and Patients with Coronary Heart Disease

Left Ventricular Systolic and Diastolic Function during Coronary Arteriography before and after Acute Left Ventricular Failure in Dogs

Contact Info

Product

Resources

About