A Study of the Mineral Environment of Caries-Resistant Navy Recruits

The concentration of aluminium and strontium was determined (by AAS) in soil (total and exchangeable), drinking water and dental enamel from an area (Zemunik) with low caries prevalence (DMFT < 2). For comparison purposes, similar samples were collected and analyzed from another village (Novigrad) in the same region with normal caries prevalence (DMFT > 5). A positive correlation between low caries prevalence and a higher concentration of strontium in soil (exchangeable form), drinking water and enamel was found. The distribution of strontium in dental enamel was shown to be fairly uniform. The concentration of aluminium in drinking water and the exchangeable form in soil was higher in the area of Zemunik.

Section: Analysis Of Dental Enamelmentioning

confidence: 99%

Dental Caries and the Concentration of Aluminium and Strontium in Enamel

Vrbic¹,

Štupar²

1980

“…A suggested association of low caries prevalence and strontium (Sr) in water sup plies by Lôdrop [1953], and later by Losee and Adkins [1969] has subsequently been substantiated by further epidemiologic stud ies [Curzon el al., 1970[Curzon el al., , 1978. Attempts to prevent caries in experimental animals by using Sr by injection, or via the food and water, however, have been equivocal with both increases and decreases in caries being reported.…”

mentioning

confidence: 99%

Pre- or Post-Eruptive Effects of Strontium Alone or in Combination with Fluoride on Dental Caries in the Rat

Meyerowitz¹,

Spector²,

Curzon³

1979

Doses of strontium were given pre-eruptively to rats at 0.0, 2.5, 5.0 and 10.0 μg Sr/10 g body weight, with or without fluoride at 1.0 μg/l0 g body weight by esophageal intubation. In a second experiment strontium at concentrations of 0, 50, 100 and 150 mg Sr/l, with and without fluoride at 10 mg/l, were given via the drinking water post-eruptively. Caries scores were made for buccolingual, morsal, sulcal und proximal lesions in all rats. Slight reductions in buccolingual caries scores were seen in rats given 5.0 μg Sr/10 g body weight pre-eruptively. Rats given post-eruptive doses of strontium only showed marked reductions in buccolingual scores with 50 mg Sr/l, and 10 mg F/l. No effect was seen on morsal, sulcal or proximal caries scores for any of the treatment regimens. The greatest reductions in buccolingual caries scores were found when a combination of 50 mg Sr/l and 10 mg F/l was given post-eruptively.

“…[Sr] in water in this area was estimated at 0.33 ppm and therefore extremely low in comparison to later studies (see below), During a sA study on caries-resistant navy recruits [Losee and Adkins, 1969], which was perhaps was the key study that sparked the interest in Sr in the caries research community in the 1970ies, it was able possible to correlate the high number of caries-resistant recruits from NW Ohio (USA) with the simultaneous occurrence of elevated [B], [Li], [Mo], [Sr] in NW Ohio water in combination with F. A median [Sr] of 6100 ppm was found in the water of the study area and the transfer of F, Li, Mo and Sr from water to green beans during cooking was shown.…”

Section: Epidemiological Caries Studiesmentioning

confidence: 62%

Strontium and Caries: A Long and Complicated Relationship

Lippert

Hara²

2012

Investigations into the role of strontium (Sr) in caries prevention have attracted great interest in the research community in the past, with its peak in the 1970-and 80ies. To this date, no clear indication of the relative importance of Sr in caries prevention has been provided. A vast number of animal caries, epidemiological and mechanistic studies have been conducted. Albeit Although a great level ofthere is much discrepancyexists in the literature, the majority of studies suggest that Sr exhibits some cariostatic properties and, predominantly in the presence of fluoride (F). An optimum Sr concentration of 5 to 10 ppm in drinking water has been proposed as a direct result of several epidemiological caries studies. Despite these results, no direct link can be established between Sr and caries prevention as, to date, no relevant, randomized control trials have been reported. The extrapolation of potential cariostatic properties of Sr from epidemiological studies is difficult due to the co-presence of several other trace elements in the water of the study areas, with many of these elements being attributed cariostatic properties in their own right.