2023
DOI: 10.1002/ame2.12319
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A study of the influence of genetic variance and sex on the density and thickness of the calvarial bone in collaborative cross mice

Uriel Kaspersky,
Roei Levy,
Aysar Nashef
et al.

Abstract: BackgroundBone microarchitecture is affected by multiple genes, each having a small effect on the external appearance. It is thus challenging to characterize the genes and their specific effect on bone thickness and porosity. The purpose of this study was to assess the heritability and the genetic variation effect, as well as the sex effect on the calvarial bone thickness (Ca.Th) and calvarial porosity (%PoV) using the Collaborative Cross (CC) mouse population.MethodsIn the study we examined the parietal bones… Show more

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