A Study of the Genetic Structure of Hybrid Camels in Kazakhstan

Abstract

Camel farming is gaining scientific interest due to its unique agricultural characteristics. Camels are versatile for milk and meat production, wool, racing, transport, and tourism. To use their full potential, it is essential to improve our understanding of the genetic structure of these animals. One-humped and two-humped camels have received detailed genetic descriptions, while there is no such information for their hybrids, which outperform their parent species in several agricultural characteristics. Thus, in this study, for the first time, the whole genome sequencing data (WGS) of five hybrid camels bred in the Almaty region of Kazakhstan are presented in comparison with the WGS data of one-humped, two-humped, and wild camels. A total of 43,552,164 single-nucleotide polymorphisms were found across the studied groups. Further comparison of these SNPs showed the following number of private SNPs among the populations: hybrid camels (3,271,083), wild camels (2,515,591), Bactrians (1,244,694), and dromedaries (531,224). The genetic structure of the studied animals was described, and a phylogenetic tree was built to assess their genetic distance. It was found that the studied hybrids are genetically closer to dromedaries since they were on the close branch of the phylogenetic tree.

Cholecystokinin‐mediated effect of insulin pathway on the steroidogenic activity of follicular granulosa cells in Camelus bactrianus: In vitro study

“…It is a unique animal in desert and semi-desert areas as it can survive under harsh environmental condition (Li et al, 2023). Among factors that reduce the reproductive performance of Camelus bactrianu are delayed age of puberty, short breeding season, prolonged gestation period and high embryonic mortality (Amandykova et al, 2023;Wang et al, 2020).…”

“…It is a unique animal in desert and semi-desert areas as it can survive under harsh environmental condition (Li et al, 2023). Among factors that reduce the reproductive performance of Camelus bactrianu are delayed age of puberty, short breeding season, prolonged gestation period and high embryonic mortality (Amandykova et al, 2023;Wang et al, 2020).Therefore, exploring the regulatory factors affecting the reproduction of Camelus bactrianus is of great significance for improving their reproductive performance.CCK is initially a gut hormone (Spirichev et al, 2023) and later detected in the central nervous system (CNS) (Lavi et al, 2004), reproductive system (Comninos et al, 2014) and endocrine system (Cherl et al, 2023). The biological effects of CCK are mediated by the interaction between two different subtypes of receptors, CCK-A and CCK-B (Honda et al, 1993).…”