A study of the association between plasma interleukin-21 gene polymorphism and the susceptibility to rheumatoid arthritis in Egyptian patients
Soheir Abdelsamea,
Rana Khashaba,
Arwa Amer
et al.
Abstract:Background: Rheumatoid arthritis (RA) is a chronic, autoimmune inflammatory illness. Proinflammatory cytokines play a crucial role in the development of RA by inducing an inflammatory response. One of these cytokines is interleukin-21 (IL-21), which regulates B-cell proliferation, plasma differentiation, and immunoglobulin synthesis; consequently, IL-21's actions on B cells may take part in the development of autoimmune disorders. Aim of the study: to investigate the association between plasma IL-21 gene polym… Show more
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