A Study of Serum Electrolytes in Severe Acute Malnourished Children With and Without Complications

Dakshayani, B; Ravi, M.D.; Premalatha, R.

doi:10.32677/ijch.2018.v05.i02.012

Cited by 3 publications

(3 citation statements)

References 7 publications

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“…Out of 100 patients in our study group, 14% had hypernatremia, while 11% had hyponatremia. A nearly similar distribution of hyponatremia in 11% and hypernatremia in 8.2% was found in the study by Tariq et al Hyponatremia was seen in 43.4% in the study by Dakshayani et al [ 15 ]. In the study by Meshram et al, hyponatremic children with SAM presented with dysnatremia in the form of hyponatremia in 56% and hypernatremia in 1.4% [ 16 ].…”

Section: Discussionsupporting

confidence: 76%

“…Mortality among those with normal potassium levels was less than 4%; however, when serum potassium levels were altered, mortality increased to about 50% in cases with hyperkalemia and 17% in cases with hypokalemia. Hypokalemia was observed at 7.1% in Dakshayani et al's study [ 15 ]. In a study by Alasad et al on the role of potassium in childhood mortality secondary to SAM, hypokalemia was evident in 70.2% of the patients and mortality was 3.1% in normokalemic and 13.9% in hypokalemic patients [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

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Prognostic Significance of Serum Biochemistry Profile in Children With Severe Acute Malnutrition

Verma¹,

Yadv²,

Chand³

et al. 2022

Cureus

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BackgroundMalnutrition is a condition caused by defective nutrition in which either deficiency or excess of energy, protein, or micronutrients cause any measurable adverse effects on tissues/body form (body shape, size, composition), function, and clinical outcome. Children with a weight-for-height below -3 standard deviations (SD) of the mean based on the WHO standards have a high risk of death exceeding nine-fold that of children with a weight-for-height above 1 SD. In severe acute malnutrition (SAM) liver function tests, renal function tests, and serum electrolytes are deranged but their correlation with the prognosis is not well defined. So, there was a need for a study to know the prognostic significance. For this purpose, the current study was conducted in the pediatric ward of

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Section: Discussionsupporting

confidence: 76%

Section: Discussionmentioning

confidence: 99%

Prognostic Significance of Serum Biochemistry Profile in Children With Severe Acute Malnutrition

Verma¹,

Yadv²,

Chand³

et al. 2022

Cureus

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“…[ 19 ] and Dakshayani et al . [ 20 ] A Study in Hyderabad by the National Institute of Nutrition from 1995 to 2015 showed that edematous malnutrition constitutes only 16.5% of malnourished children and led to mortality in 27.3% of malnourished children. [ 21 ] Whereas this study did not aim to identify risk factors of mortality, but we observed that edematous children were more likely to discontinue treatment and are at increase risk of death as compare to nonedematous children.…”

Section: Discussionmentioning

confidence: 99%

Clinico-biochemical profile of sick children with severe acute malnutrition

Kumar

Rao

Singh

2020

J Family Med Prim Care

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Objective: Severe acute malnutrition (SAM) classified as edematous and marasmus, however, Kwashiorker represents the most severe phenotype of edematous malnutrition. The aim of this study was to describe the clinico-biochemical profile in sick children with severe acute malnutrition. Materials and Methods: This is a descriptive cross-sectional study, which included children aged 6 to 60 months, fulfilling the World Health Organization (WHO) criteria of severe acute malnutrition. We collected data on demography, anthropometry, history, and clinical examination. Investigations included arterial blood gas analysis, serum electrolytes, calcium, serum albumin, and blood sugar. P value < 0.05 was considered significant. Results: One hundred twenty-two children with SAM were recruited, out of which 65 (53.27%) had edematous malnutrition and 57 (46.7%) had nonedematous malnutrition. Out of total children, 90 (73.77%) were discharged from hospital, 18 (14.7%) died, and 14 (11.4%) were left against medical advice. Out of 122 children with SAM, edematous children were younger (25.7 vs. 34.5 months, P = 0.002). Children with edematous malnutrition were more likely to have pneumonia ( P = 0.04), acute gastroenteritis ( P < 0.001), hyponatremia ( P = 0.04), metabolic acidosis ( P = 0.005), and hypocalcemia ( P = 0.006) when compared with nonedematous children. Edematous malnutrition has 1.3 and 1.4 times more risk of death and leave against medical advice (LAMA) respectively as compared to nonedematous malnutrition. Mortality was higher in edematous malnutrition (12, 66.6%) than nonedematous malnutrition (6, 33.3%). Conclusion: Edematous malnutrition was commonly prevalent in 1 to 3 years of children and clinical and biochemical abnormalities frequently co-exist with edematous malnutrition.

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Micronutrient status in children aged 6–59 months with severe wasting and/or nutritional edema: implications for nutritional rehabilitation formulations

Vresk,

Flanagan,

Daniel

et al. 2024

Nutrition Reviews

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Undernutrition remains a global struggle and is associated with almost 45% of deaths in children younger than 5 years. Despite advances in management of severe wasting (though less so for nutritional edema), full and sustained recovery remains elusive. Children with severe wasting and/or nutritional edema (also commonly referred to as severe acute malnutrition and part of the umbrella term “severe malnutrition”) continue to have a high mortality rate. This suggests a likely multifactorial etiology that may include micronutrient deficiency. Micronutrients are currently provided in therapeutic foods at levels based on expert opinion, with few supportive studies of high quality having been conducted. This narrative review looks at the knowledge base on micronutrient deficiencies in children aged 6–59 months who have severe wasting and/or nutritional edema, in addition to highlighting areas where further research is warranted (See “Future Directions” section).

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A Study of Serum Electrolytes in Severe Acute Malnourished Children With and Without Complications

Cited by 3 publications

References 7 publications

Prognostic Significance of Serum Biochemistry Profile in Children With Severe Acute Malnutrition

Prognostic Significance of Serum Biochemistry Profile in Children With Severe Acute Malnutrition

Clinico-biochemical profile of sick children with severe acute malnutrition

Micronutrient status in children aged 6–59 months with severe wasting and/or nutritional edema: implications for nutritional rehabilitation formulations

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