2024
DOI: 10.1371/journal.pone.0296187
|View full text |Cite
|
Sign up to set email alerts
|

A study of roflumilast treatment on functional and structural changes in hippocampus in depressed Adult male Wistar rats

Ghida Hassan,
Sherif A. Kamar,
Hagar Yousry Rady
et al.

Abstract: Depression is a common stress disability disorder that affects higher mental functions including emotion, cognition, and behavior. It may be mediated by inflammatory cytokines that interfere with neuroendocrine function, and synaptic plasticity. Therefore, reductions in inflammation might contribute to treatment response. The current study aims to evaluate the role of Protein Kinase (PKA)- cAMP response element-binding protein (CREB)- brain derived neurotropic factor (BDNF) signaling pathway in depression and … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 2 publications
references
References 63 publications
0
0
0
Order By: Relevance