A study of prescribing pattern of drugs in patients of cardiovascular emergencies at a tertiary care hospital of Western Maharashtra

Vakade, Kiran Prabhakar; Thorat, Vandana M.; Khanwelkar, Chitra C.; Jadhav, Smita; Sanghishetti, Vijayprasad M.

doi:10.18203/2320-6012.ijrms20160314

Cited by 11 publications

(11 citation statements)

References 14 publications

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“…This shows similarity with study by Vakade et al (5.85 days) and Aswani et al (5.33days). 9,14 Ischaemic heart disease accounted for 41% of the patients while 24% of patients had CVA, this is comparable to study conducted by Hannan et al (96.75%) and Rathod et al (41.59%). 15,16 In this study we also found that the average number of drugs prescribed per patient was 5.08 ±2.5, indicating polypharmacy, similar results were seen in the study of Aswani et al (5.58) and Kaur et al (4.9) but studies by Al junid et al showed a higher incidence (7.56±3.37).…”

Section: (2455%)supporting

confidence: 82%

Study of utilisation trends of drugs in patients admitted with cardiovascular diseases at a tertiary care hospital in Goa

Kerkar

Bhandare

2017

Int J Sci Rep

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Background: CVDs have emerged as a leading cause of mortality and morbidity in the world as well as in India. Drug usage is life saving and at times many drugs may be needed. Drug utilization studies aid to find the appropriateness of treatment, identify shortcomings if any, and provide a feedback to the healthcare providers to improve their management with drugs. So such types of studies are of vital importance in every hospital.Methods: This was a prospective, observational study of 180 patients with CVDs admitted in medicine and cardiology wards of a tertiary care hospital, conducted through case records and patients’ interviews. Data was represented as mean±SD, number and frequency. Results: Incidence of cardiovascular diseases was more in males (56.67%) than the females (43.33%). Average number of drugs prescribed per patient was 9.16 and that of cardiovascular drugs was 5.08 ± 2.15. Antiplatelets (88.88%) were the most commonly prescribed cardiovascular drugs followed by hypolipidemics (82.22%). About 15.06% of injectables and 1.2% of fixed dose combinations (FDCs) were prescribed. Drugs prescribed by generic names were 1.6% and those from the National List of Essential Medicines were 92.79%.Conclusions: The results of this study suggested: polypharmacy, overuse of injections and low prescribing habits from essential drug list. Though antiplatelet, hypolipidemic use was higher, these are an essential part of treatment of certain CVDs.

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Section: (2455%)supporting

confidence: 82%

Study of utilisation trends of drugs in patients admitted with cardiovascular diseases at a tertiary care hospital in Goa

Kerkar

Bhandare

2017

Int J Sci Rep

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“…Out of 91 MI cases, 56 (61.53%) were male and 35 (38.46%) were female. Most common comorbid conditions found in patients were hypertension 94 (62.66%) and diabetes mellitus 23 (15.33%), this observation was similar to those of H. Nagabhushan et al, and Pendhari SR et al 5,6 Most common cardiovascular emergency was found to be MI 91 (60.66%) followed by Angina pectoris 37 (24.66%), which were in agreement with the study conducted by Vakade KP et al 7 Hypolipidemics 142 (94.66%) and antiplatelets 139 (92.66%) followed by anticoagulants 80 (53.33%) were the most commonly prescribed drug classes. These results are in accordance with Kerkar SS et al, and Nagabhushan H et al 4,5 Apart from these; drug utilization rate of diuretics, beta blockers, ACE inhibitors were also seemed to be high.…”

Section: Resultssupporting

confidence: 88%

Study of drug utilization in cardiovascular emergency at a rural teaching hospital in Tamilnadu, India

Fardan¹,

Manjari²,

Periasamy³

2019

Int J Basic Clin Pharmacol

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Background: Cardiovascular disease is a common term which encompasses a range of disorders that affect the heart. Cardiovascular disease is the leading cause of death among men and women in India and across the globe. There is evidence of irrational drug use in cardiovascular disorders. Drug utilization study is used to evaluate the rationality of medication use. The objective of this study was to observe the most frequently treated emergency cardiovascular diseases and to study the prescribing pattern among inpatients admitted in CICU Unit of tertiary care teaching hospital.Methods: A retrospective, observational drug utilization study was designed to evaluate the drug prescribing pattern in cardiovascular emergency patients admitted in CICU unit of tertiary care teaching hospital. Study was carried out for a duration of 4 months. Data were collected from patient case reports after getting permission from Medical superintendent of hospital. Prescribing pattern of drugs were studied based on WHO indicators.Results: Total 150 patients were included in the study. Most common cardiovascular emergency reported was Myocardial infarction (60.66%) followed by Angina pectoris (24.66%). The most common comorbidities found along with cardiovascular emergency were hypertension (62.66%) followed by Diabetes mellitus (15.33%). Most prescribed cardiovascular drugs were from the category of hypolipidemics (94.66%) and anti-platelets (92.66%). Average number of drugs per prescription was found to be 9.42. Average hospital stay per patient was found to be 4.25 days. Percentage of drugs prescribed by generic name was 70.66%. Percentage of drugs prescribed from essential drug list and National list of essential medicines were 87.4% and 97.23% respectively.Conclusions: All the drugs prescribed were according to the current guidelines. Majority of the drugs were prescribed in generic form.

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“…In the current study, the results reveal that of 100 patients, the frequency of the use of ACEIs and ARBs was more in male patients (77.0%) than female patients (23.0%). Similar results were shown in accordance with the study conducted by Vakade et al [14]. However, contradictory results were shown by the study conducted by Barrron et al [15].…”

Section: Discussionsupporting

confidence: 90%

“…Among the ACEIs, perindopril was most commonly used followed by lisinopril and ramipril [21]. According to the study conducted by Vakade et al [14], olmesartan was the commonly used ARBs.…”

Section: Discussionmentioning

confidence: 99%

A Study on Utilization of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Patients With Cardiovascular Diseases

Sood

Joseph

Mathew

et al. 2018

Asian J Pharm Clin Res

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Objectives:The objective of this study was to assess the prescribing pattern, most common indication, and adverse effects associated with angiotensinconverting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) in patients with cardiovascular diseases, and to identify the risk factors associated with cardiovascular diseases in a tertiary care hospital.Methods: A prospective observational study was carried out for a period of 6 months from October 2016 to March 2017 in both inpatients and outpatients of the cardiology department. Patients received either ACEIs or ARBs were enrolled in the study. The relevant details of the patients were collected from the patient case note and treatment chart and data analyzed.Results: Of 100 patients, 23.0% were female and 77.0% were male. Among them, majority of patients were in the age group of 41-60 years. Diabetes mellitus (39%), smoking (20%), and alcohol (14%) were the common risk factors. The most common indications of ACEIs were found to be ischemic heart diseases (IHDs) (17%) followed by hypertension (HTN)/IHD (12%), and IHD/heart failure (12%). Main indications of ARBs were found in HTN/ IHD (16%). Utilization of ACEIs (70%) was found to be higher when compared with ARBs (30%). Ramipril (69%) and telmisartan (18%) were the most commonly used ACEIs and ARBs, respectively. While analyzing the adverse effects of ACEIs and ARBs, about 5.71% of patients were identified with ramipril induced dry cough. Conclusions:The complications of cardiovascular diseases can be reduced by knowing the incidence of risk factors and alternative therapy can be initiated by assessing the incidence of adverse drug reactions related to ACEIs and ARBs

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A study of prescribing pattern of drugs in patients of cardiovascular emergencies at a tertiary care hospital of Western Maharashtra

Cited by 11 publications

References 14 publications

Study of utilisation trends of drugs in patients admitted with cardiovascular diseases at a tertiary care hospital in Goa

Study of utilisation trends of drugs in patients admitted with cardiovascular diseases at a tertiary care hospital in Goa

Study of drug utilization in cardiovascular emergency at a rural teaching hospital in Tamilnadu, India

A Study on Utilization of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Patients With Cardiovascular Diseases

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