A study of patients with type II respiratory failure put on non-invasive positive pressure ventilation

Vanani, Vishal; Patel, Monila

doi:10.4103/1755-6783.121015

Cited by 8 publications

(6 citation statements)

References 20 publications

(40 reference statements)

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“…No mortality was observed in the patients improved and continued on NIPPV. The success rate in the present study is comparable with the previous studies 14,15,16,27,30 In our study NIPPV was used for a mean duration of 38.5±13 hrs. In the study of Umberto Meduri et al 31 it was 23±17 hrs.…”

Section: Discussionsupporting

confidence: 91%

“…In the present study there was a significant improvement (P<0.0001) in the average PaCO2 levels within 1hr from 67.3± 5.61 to 62.8±5.74. The results obtained are comparable with the other studies 14,16,26 which showed significant decrease in PaCO2 after 1hr of administration of NIV. The change in PaCO2 also reflected in pH with improvements from 7.29±0.02 to 7.31±0.02 (p<0.001).…”

Section: Discussionsupporting

confidence: 90%

“…14,15 (Table 1) The present study group has a male preponderance (36/40) of 90% similar to other studies. 15,16,17 ( Table 2). The most common indication of NIV in our Study was acute exacerbation of chronic obstructive pulmonary disease (AE-COPD)90 % (Table 3) as in other studies 14,15,18 NIV was successful in 83.3% of patients in our study cohort of Acute exacerbation of COPD.…”

Section: Discussionmentioning

confidence: 99%

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Experience With Non - Invasive Ventilation in Type Ii Respiratory Failure at Department of Pulmonary Medicine, Kurnool Medical College, Kurnool

Sailaja¹,

Bharat²,

H³

et al. 2015

jebmh

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BACKGROUND: Non-invasive ventilation (NIV) is the delivery of positive pressure ventilation through an interface to upper airways without using the invasive airway. Use of NIV is becoming common with the increasing recognition of its benefits. OBJECTIVES: This study was done to evaluate the feasibility and outcome of NIV (BiPAP) in Type II Respiratory Failure in Department of Pulmonary Medicine, Kurnool Medical College. Materials and Methods: An observational study conducted over a period of 18 months in Department of pulmonary medicine, Kurnool Medical College in 40 patients who were treated by NIV (BiPaP). Patients were stratified on basis of set of exclusion and inclusion criteria. NIV was given in accordance with the arterial blood gas (ABG) parameters defining Type II respiratory failure. RESULTS: In the present study NIPPV was successful in 34(85%) and failed in 6(15%) patients. The most common indication of NIV in our hospital was acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) 90% and 88% of AE-COPD patients were improved by NIV. Application of NIV resulted in significant improvement of pH and blood gases in COPD patients. Kyphoscoliosis, Obstructive Sleep Apnea (OSA) patients with Type II Respiratory failure also showed significant improvement in partial pressure of oxygen and carbon dioxide. CONCLUSION: This study demonstrates and encourages the use of NIV as the first-line ventilator treatment in AE-COPD patients with Type II respiratory failure. It also supports NIV usage in other causes of type II Respiratory failure as a promising step toward prevention of mechanical ventilation.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

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Experience With Non - Invasive Ventilation in Type Ii Respiratory Failure at Department of Pulmonary Medicine, Kurnool Medical College, Kurnool

Sailaja¹,

Bharat²,

H³

et al. 2015

jebmh

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“…Respiratory rate at admission was significantly higher in the NIPPV failed group as compared with the NIPPV successful group, and this could possibly be used to predict response to NIPPV [23,24].…”

Section: Discussionmentioning

confidence: 95%

Effectiveness of non invasive positive pressure ventilation in chronic obstructive pulmonary disease patients

Soliman

Elshazly

Soliman

et al. 2014

Egyptian Journal of Chest Diseases and Tuberculosis

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27 patients diagnosed as chronic obstructive pulmonary disease (COPD) came with acute hypercapnic respiratory failure due to COPD and met the inclusion and exclusion criteria. They were managed by non invasive positive pressure ventilation (NIPPV). 21 cases showed success and 6 cases showed failure and were put on invasive mechanical ventilation within the first 24 h. It was shown that before initiation of NIPPV, the failed cases had significantly higher Body Mass Index (BMI) 34.7 compared to 28.1 in successful cases and significantly lower pH 7.20 ± 0.05 compared with 7.27 ± 0.04. After 1 h of initiation of NIPPV, the successful group showed improvement regarding pH and PaCO 2 , while the failed group showed worsening of the same parameters, with a significant difference (p value <0.001, 0.005), respectively. After 4 h, there was improvement in both groups regarding pH which reached normalization in the successful group, PaCO 2 , and PO 2 , with no statistical significant difference. There were significant differences in the respiratory rate (p value < 0.001), and the expiratory positive airway pressure (EPAP) (p value 0.024) between the two groups. Thus we can conclude that the use of NIPPV in such patients can be successful in around 78% of cases, however failure can be predicted by high BMI, initial lower pH and higher PaCO 2 , insignificant response to NIPPV after 1 h. They also show increased respiratory rate and need for higher expiratory positive airway pressure.

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“…In present study, mean age among the study population was 49.40 (±9.89) years, Similarly, in the studies by George et al [16] and Lt. Col. Rai et al [17] , the average age of patients enrolled was >50 years. The present study has a male preponderance (68/110) of 61.8%; the study of Agrawal et al [18] and Vanani et al [19] , had a male preponderance of 63% and 86% respectively. The common indication for initiation of NIPPV was COPD 37 (33.63%) followed by Postextubation 30 (27.27%) in present study.…”

Section: Discussionmentioning

confidence: 86%

Effectiveness of Noninvasive Positive Pressure Ventilation in the Management of Acute Respiratory Failure

A¹

2017

JMSCR

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A study of patients with type II respiratory failure put on non-invasive positive pressure ventilation

Cited by 8 publications

References 20 publications

Experience With Non - Invasive Ventilation in Type Ii Respiratory Failure at Department of Pulmonary Medicine, Kurnool Medical College, Kurnool

Experience With Non - Invasive Ventilation in Type Ii Respiratory Failure at Department of Pulmonary Medicine, Kurnool Medical College, Kurnool

Effectiveness of non invasive positive pressure ventilation in chronic obstructive pulmonary disease patients

Effectiveness of Noninvasive Positive Pressure Ventilation in the Management of Acute Respiratory Failure

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