A Study of Inappropriate Dosing of Antibacterial Agents in Consideration with Estimated G.F.R Values

Shalini, .; Agarwal, Sanjit; Mc, Joshi

doi:10.5958/j.0976-5506.4.4.167

Cited by 1 publication

(10 citation statements)

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“…Modification of Diet in Renal Disease (MDRD) was used in eight studies (Holm et al, 2015, Markota et al, 2009, Nielsen et al, 2013, Saleem and Masood, 2016, Shalini et al, 2013, Sharif-Askari et al, 2014, Sheen et al, 2007, Shigematsu et al, 2017; seven studies used Cockcroft-Gault (CG) CG (Getachew et al, 2015, Juarez-Cedillo et al, 2016, Prajapati and Ganguly, 2013, Sweileh et al, 2007, Taner et al, 2018, Yang et al, 2016, Won et al, 2018; A combination of MDRD and CG was used in three studies (Manjula Devi et al, 2014, O'Shaughnessy et al, 2017, Gomez-Lobon et al, 2012; while two studies did not report the method (Garedow et al, 2019, Saleem et al, 2017, (Table .1)…”

Section: Methods Of Estimating Kidney Functionmentioning

confidence: 99%

“…Seven studies used one source (Getachew et al, 2015, Nielsen et al, 2013, Prajapati and Ganguly, 2013, Saleem et al, 2017, Yang et al, 2016, Gomez-Lobon et al, 2012, Won et al, 2018. Nine studies used two or more sources (Holm et al, 2015, Manjula Devi et al, 2014, Markota et al, 2009, O'Shaughnessy et al, 2017, Shalini et al, 2013, Sharif-Askari et al, 2014, Sweileh et al, 2007, Sheen et al, 2007, Garedow et al, 2019. Two studies used combination of resources Masood, 2016, Juarez-Cedillo et al, 2016), whereas one study did not report (Taner et al, 2018).…”

Section: Methods and Resources Used In Identifying Drpsmentioning

confidence: 99%

“…Two studies used combination of resources Masood, 2016, Juarez-Cedillo et al, 2016), whereas one study did not report (Taner et al, 2018). The most frequently used prescribing information sources were the BNF (n=4) (O'Shaughnessy et al, 2017, Saleem and Masood, 2016, Shalini et al, 2013, Sharif-Askari et al, 2014, the Renal Drug Handbook (RDH) (n=2) (Holm et al, 2015, O'Shaughnessy et al, 2017, and Micromedex, a collection of drug information databases (n=3) (Saleem et al, 2017, Manjula Devi et al, 2014, Gomez-Lobon et al, 2012, (Table 1).…”

Section: Methods and Resources Used In Identifying Drpsmentioning

confidence: 99%

“…Inappropriate sampling frame was apparent in eight studies (Sweileh et al, 2007, Prajapati and Ganguly, 2013, Manjula Devi et al, 2014, Juarez-Cedillo et al, 2016, O'Shaughnessy et al, 2017, Getachew et al, 2015, Yang et al, 2016, Won et al, 2018. Further analysis was needed in eight studies (Sheen et al, 2007, Markota et al, 2009, Gomez-Lobon et al, 2012, Shalini et al, 2013, Nielsen et al, 2013, Manjula Devi et al, 2014, Juarez-Cedillo et al, 2016, Yang et al, 2016 (appendix-1).…”

Section: Quality Assessmentmentioning

confidence: 99%

“…The majority of studies (60%) were conducted in Asia (Manjula Devi et al, 2014, Prajapati and Ganguly, 2013, Saleem and Masood, 2016, Saleem et al, 2017, Shalini et al, 2013, Sharif-Askari et al, 2014, Sheen et al, 2007, Sweileh et al, 2007, Shigematsu et al, 2017, Taner et al, 2018, Yang et al, 2016, Won et al, 2018, followed by Europe (25%) (Holm et al, 2015, Markota et al, 2009, Nielsen et al, 2013, O'Shaughnessy et al, 2017, Gomez-Lobon et al, 2012, Africa (10%) (Getachew et al, 2015, Garedow et al, 2019 and one in North America (5%) (Juarez-Cedillo et al, 2016). Most (n = 17) of the studies were carried out in different hospital departments while three were conducted in nephrology units only (Saleem and Masood, 2016, Saleem et al, 2017, Sharif-Askari et al, 2014.…”

Section: Settings and Countriesmentioning

confidence: 99%

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Drug-Related Problems in Hospitalised Patients with Chronic Kidney Disease: A Systematic Review

et al. 2021

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Introduction:Globally, Chronic Kidney Disease (CKD) is one of the leading causes of mortality.Impaired renal function makes CKD patients vulnerable to drug-related problems (DRPs). AimThe aim of this systematic review was to investigate the prevalence and nature of DRPs among hospital in-patients with CKD. MethodsA systematic review of the literature was conducted using Medline, EMBASE, PsycINFO, Web of Science (Core Collection), CINAHL plus (EBSCO), Cochrane Library (Wiley), Scopus (ELSEVIER) and PubMed (U.S.NLM) from index inception to January 2020. Studies investigating DRPs in hospitalised CKD patients published in English language were included. Two independent reviewers extracted the data and undertook quality assessment using Joanna Briggs Institute (JBI) tool. ResultsA total of 2895 unique titles were identified; with 20 meeting the inclusion criteria.DRPs prevalence in CKD was reported between 12% to 87%. The most common DRPs included ineffective treatment, inappropriate drug choice, and dosing problems.Antibiotics, H2-antihistamine and oral antidiabetics (metformin) were common drug classes involved in DRPs. Factors associated with DRPs included severity of CKD, the number of medications taken, age, length of hospital stay, and gender. ConclusionThis systematic review provides evidence that DRPs are a frequent occurrence and burden for hospitalised patients with stage 1-4 CKD. Heterogeneity in study design, case detection and definitions are common, and future studies should have use clearer definitions and study designs.

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