A Study of Growth in Iranian Village Children

Ronaghy, Hossain A.; Caughey, J. E.; Halsted, James A.

doi:10.1093/ajcn/21.5.488

Cited by 28 publications

(7 citation statements)

References 13 publications

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“…In contrast with expectations, the effect of birth weight was eliminated when the data were placed in a regression equation, even though an association has been reported between low birth weight and subsequent childhood malnutrition in other reviewed studies 5,12,14–16. It seems that maternal height as a predisposing factor affecting childhood birth weight is the strongest risk factor, and therefore the effect of birth weight was modified or neutralized in the regression equation.…”

Section: Discussionmentioning

confidence: 90%

Evaluating risk factors for protein-energy malnutrition in children under the age of six years: a case-control study from Iran

Sharghi

Ali²,

Faridan³

2011

IJGM

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Introduction:Protein-energy malnutrition is one of the most important public health problems in Iran. It not only accounts for more than half of child mortality but can also produce somatic and mental impairment in survivors. The main aim of this study was to identify risk factors for protein-energy malnutrition in children under 6 years of age in Namin city.Methods:This was a population-based, multicenter case-control study. Seventy-six children with malnutrition and 76 children without malnutrition were randomly recruited for case and control groups. The prevalence of risk factors in the two groups was compared. Data were gathered from a health center database and interviews with mothers and health workers. The Wilcoxon signed-rank test and logistic regression were used for data analysis.Results:Female gender, poverty, short maternal height, and use of unhygienic latrines in the home were significantly associated with childhood malnutrition (P < 0.05).Conclusion:The results of this study indicate four main factors (poverty, small maternal height, female gender, and absence of hygienic latrines in the home) as underlying factors in malnutrition of children under the age of 6 years.

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Section: Discussionmentioning

confidence: 90%

Evaluating risk factors for protein-energy malnutrition in children under the age of six years: a case-control study from Iran

Sharghi

Ali²,

Faridan³

2011

IJGM

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“…The impact of zinc on growth was first described in humans in adolescent populations in Iran and Egypt [35,36]. In these studies of young adults who presented with a syndrome characterized by varying degrees of growth stunting and delayed sexual maturation (hypogonadal dwarfism), treatment with zinc induced accelerated growth and commencement of sexual maturation in most participants [36,37]. However, this response was not duplicated in a population of stunted and sexually delayed adolescents in a different area of Egypt [38], possibly because of other limiting nutrients in their diets.…”

Section: Physical Growthmentioning

confidence: 99%

The Importance of Zinc in Human Nutrition and Estimation of the Global Prevalence of Zinc Deficiency

2001

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This paper summarizes recent research on the importance of zinc for human health, and reviews available methods of evaluating zinc status in individuals and populations. The lack of generally accepted biomarkers of zinc status has impeded estimation of the global prevalence of zinc deficiency. Although measurement of zinc consumption and/or plasma zinc concentration can be used to assess population zinc status, few countries have collected adequate data to permit estimation of the prevalence of zinc deficiency. An alternative method, described herein, is to estimate the zinc content of national food supplies, using FAO food balance sheets; the assumed bioavailability of that zinc based on phytate:zinc molar ratios; and the relation between absorbable zinc and theoretical requirements according to country-specific demographics. The results of these analyses indicate that nearly half of the world's population is at risk for inadequate zinc intake, suggesting that public health programs are urgently needed to control zinc deficiency.

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“…Zinc had no apparent effect on growth or development. Ronaghy et al (57) confirmed these findings in Iranian middle school village boys.…”

Section: Current Status Of Knowledgementioning

confidence: 72%

Human Zinc Deficiency: Discovery to Initial Translation

Sandstead

2013

Advances in Nutrition

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Ananda S Prasad first suspected zinc deficiency in 1958 after he, at the request of James A Halsted, evaluated a patient with severe iron deficiency. In addition to iron deficiency, the patient appeared ∼10 y old and was severely stunted and prepubertal, though his chronological and bone age were much older. He also had hepatosplenomegaly and ate clay. The condition was not rare in that 11 cases were reported. In 1961 Prasad joined the Vanderbilt Nutrition Group led by William J. Darby at the US Naval Medical Research Unit-3, Cairo, Egypt. Prasad et al. studied 40 males similar to the index case. Contrasts with the index case included no clay eating and infection with schistosomiasis and hookworm. Zinc kinetics confirmed the zinc deficiency. Endocrine studies showed hypopituitarism. Treatment with zinc and an omnivorous diet was more efficacious for growth than no treatment, diet alone, or iron and diet. Later, Halsted et al. confirmed these findings in stunted Iranian farmers. The key role of diet in the illness became evident when Prasad found 16 severely stunted farmers from 2 oases who were not infected with schistosomiasis or hookworm. Later, Reinhold et al., in Halsted's group, reported that phytate and other indigestible zinc-binding ligands in unleavened bread prepared from high-extraction wheat flour suppress zinc absorption.

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A Study of Growth in Iranian Village Children

Cited by 28 publications

References 13 publications

Evaluating risk factors for protein-energy malnutrition in children under the age of six years: a case-control study from Iran

Evaluating risk factors for protein-energy malnutrition in children under the age of six years: a case-control study from Iran

The Importance of Zinc in Human Nutrition and Estimation of the Global Prevalence of Zinc Deficiency

Human Zinc Deficiency: Discovery to Initial Translation

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