A study of gall stone disease from a tertiary care center of Madhya Pradesh, India

Abstract

Background: Gall stone precipitation is multifactorial in nature. Nowadays, gallbladder disease is a frequent problem in developed countries including India, representing a major health problem. The present study was planned to study the epidemiology of gall stone disease in the region of Madhya Pradesh, India.Methods: A retrospective cohort of patients seeking surgical care for their gall stone disease during past one year at Sukhsagar Medical College, Jabalpur, Madhya Pradesh, India during formed the study population. Study tools were records of the patients such as information from MRD department and records from histopathological section.Results: Majority (26.6%) of cases was in the age group of 51-60 years followed by 21.6% cases in the age group of 41-50 years. Sex wise 63.3% were females. Most (71.7%) patients presented with the complaints of pain in the region of hypochondrial region followed by nausea in 46.6%. Jaundice was the least common presenting feature shown by 6.6% patients. As per gross morphology, majority of cases (44) had pigmented stones. As per biochemical analysis, majority of cases (33) had mixed type of stones. The gall stones size varied from 0.2 cm to 2.2 cm in diameter. The weight of gall stones ranged from 0.34 gm to 4.9 gm.Conclusions: Cholelithiasis is more common in the age group of 41- 60 years with female predominance. Non-vegetarians are at risk for cholelithiasis compared to vegetarians. Hypochondrial pain is most common manifestation. Chronic cholecystitis was the most common histopathological diagnosis. Mixed type stones were common variety.

The Commonest Clinical Presentation of Gallstone Disease in Laparoscopically Cholecystectomized Patients

“…The association between gender and clinical presentation was assessed by applying chi square Table (2). The P-value < 0.005 is statistically signifi cant.…”

“…GS disease symptoms range between simple biliary colic and complicated symptoms (6) . Biliary colic manifested as right hypochondrial pain lasting for half an hour, is a good indication of GS disease, and is the symptom of higher frequency for symptomatic GS disease (2,7) . Recurrence of symptoms and/or complication is highly expected when biliary colic was developed.…”