A Study of Electrolyte Imbalance in Diabetic Patients at a Teritary Care Hospital in Kerala

Antony, Sunil

doi:10.5958/2321-1032.2019.00006.8

Cited by 2 publications

(2 citation statements)

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“…This result is in line with those studies in India and Iraq 42,44 but it is inconsistent with a study conducted in Kerala. 28 Elevated serum CI − levels in diabetic patients may be caused by a drop in blood pH brought by ketoacidosis, which causes an acid-base imbalance that results in elevated Cl − levels. 34 The median Ca 2+ levels were significantly reduced in participants with DM compared to control groups.…”

Section: Discussionmentioning

confidence: 99%

“… 26 However, our study finding was lower than studies done in Bangladesh (63.3%) and Kerala (75%). 27 , 28 The difference could be those studies done in admitted diabetic patients included diuretics medication takers and the majority of participants had diabetic nephropathy, both of which are major contributors to hyponatremia. This study also showed that there was hypernatremia of 11.4% [95% CI: 7.02–18.3] due to osmotic diuresis increasing urination if the water is not replaced sufficiently leading to hypernatremia.…”

Section: Discussionmentioning

confidence: 99%

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Assessment of Electrolyte Imbalance and Associated Factors Among Adult Diabetic Patients Attending the University of Gondar Comprehensive Specialized Hospital, Ethiopia: A Comparative Cross-Sectional Study

Eshetu¹,

Worede²,

Fentie³

et al. 2023

DMSO

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Introduction: Electrolyte imbalance refers to altered electrolyte levels that predominantly affect diabetic patients due to hyperglycemia which rise plasma osmolality and impaired renal function, contributing to a change in electrolyte level. Therefore, this study aimed to assess the prevalence of electrolyte imbalance and its associated factors among diabetic patients and healthy control groups attending the University of Gondar Comprehensive Specialized Hospital. Patients and Methods: A comparative cross-sectional study was conducted on 130 diabetic patients and 130 diabetes-free controls. Sociodemographic, behavioral and clinical data were collected using a structured questionnaire. After measuring anthropometric parameters, 5mL of the blood sample was collected. Electrolytes were measured based on ion-selective electrode methods. Fasting blood glucose, and creatinine were measured by spectrophotometric enzyme hexokinase, and Jaffe reaction methods, respectively. The data was entered into Epi-data version 4.6 and analyzed using STATA version 14. Mann-Whitney U-tests and independent t-tests were used for comparison. Multiple logistic regression analysis was done to determine the factors associated with electrolyte imbalances. P-value <0.05 was considered statistically significant. Result: The overall prevalence of electrolyte imbalance among diabetic patients and controls were 83.07% and 52.31%, respectively. The mean of Na + and the median level of Mg 2+ and Ca 2+ were significantly decreased. However, the mean level of Cl − was significantly increased in diabetic patients as compared to control groups. In multivariable logistic regression: alcohol consumption AOR = 3.34 [1.02-10.9], no formal education ], hyperglycemia AOR = 6.32 [2.04-19.5], and urbanization ] showed significant association with electrolyte imbalance. Conclusion: Diabetic patients have more likely to develop electrolyte imbalance than control groups. Diabetic participants showed significantly reduced Na + , Mg 2+ , and Ca 2+ levels and significantly increasing CI − levels when compared to control groups. Hyperglycemia, alcohol drinking habits, urbanization, and no-formal education were statistically significantly associated with electrolyte imbalance.

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Section: Discussionmentioning

confidence: 99%