A Study of Electrohydraulic and Electric Pulse Methods of Contact Lithotripsy

Ivanova, L. Yu.; Chernenko, V. P.; Boshchenko, V. S.

doi:10.1007/s10527-013-9336-7

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“…A large number of clinical observations show that with the use of a focused ultrasonic wave, it is possible to destroy gallstones into small fragments that can be removed through the cystic to the bile duct into the duodenum. The period of fascination with extracorporeal lithotripsy ended in disappointment (Ivanova et al, 2013). This is due to the fact that not all fragments can be independently excreted from the bile ducts due to the weak motor activity of the bile ducts.…”

Section: Introductionmentioning

confidence: 99%

The study of the possibility of drug dissolution of gallbladder calculi

Dikman

Soldatov

Chirev

2020

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Purpose The purpose of this paper is to verify the possibility of ultrasonic intensification of drug dissolution of cholesterol calculi of the gallbladder using conventional ultrasound frequency and intensity from 0.1 to 0.5 W/cm2. Design/methodology/approach For research purposes, the physical model was developed containing pig bile, pig liver, pigskin, fat and muscles, as well as human cholesterol calculus removed by surgery and a drug with ursodeoxycholic acid. Findings The studies have shown the possibility of accelerating the drug dissolution of calculi of the gallbladder with ultrasound exposure. The ultrasound intensity of 0.4 W/cm2 is the most preferable to intensify the dissolution of calculus. Originality/value The results will be used to advance with development of the device and methodology for ultrasonic intensification of drug dissolution of gallbladder calculi.

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Section: Introductionmentioning

confidence: 99%