A Study of Eclampsia Cases Associated with Posterior Reversible Encephalopathy Syndrome

Bembalgi, Shobha; Kamate, Vishal; Shruthi, K

doi:10.7860/jcdr/2015/14039.6276

Cited by 11 publications

(13 citation statements)

References 14 publications

(8 reference statements)

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“…15 Study done by Shobhabembalgi, Fisher N et al and many case reports had reported incidence of PRES is more in postpartum period. 9,13,[16][17][18] In the present study group we observed the 73.3% and 26.7% of the patients had PRES during the antepartum and postpartum respectively and is similar to Manavi PJ study. 15 A study done by Brewer J reported that no significant difference between incidence of PRES in antepartum or postpartum eclamptic patients.…”

Section: Resultssupporting

confidence: 75%

“…Incidence of PRES in our hospital is higher (0.4%) compared to other studies. 9,14 It could be because ours is a tertiary care hospital where patients are referred from other centers and also because facilities for neuroimaging are not universally available. Incidence of PRES in eclamptic women is 54.5% in the present study as compared to 62.5% in Nelli et al study, 19.2% in Mayama study.…”

Section: Resultsmentioning

confidence: 99%

“…1,2 Most cases of PRES in obstetrics are seen in the setting of acute hypertensive encephalopathy, preeclampsia, eclampsia or nephrotic states. 1,9,10 Neuroimaging is important tool for the diagnosis of PRES and abnormalities encountered in PRES are best demonstrated by magnetic resonance imaging (MRI). 11 Typical and atypical forms of PRES have been documented.…”

Section: Resultsmentioning

confidence: 99%

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Maternal and perinatal outcome in eclampsia complicated by posterior reversible encephalopathy syndrome; a three years’ experience in a tertiary care hospital

Karanth

Gonsalves

Sheela

et al. 2017

Int J Reprod Contracept Obstet Gynecol

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Background: PRES can be associated with number of medical conditions and was observed frequently in patients with preeclampsia and eclampsia. Neuroimaging is important for the diagnosis of PRES. Study was conducted to find out the maternal and perinatal outcome in patients with eclampsia complicated by posterior reversible encephalopathy syndrome (PRES).Methods: This is a retrospective study done at St. Johns Medical College Bangalore, between October 2013 and October 2016. We reviewed case records of all the patients with eclampsia who underwent neuro imaging studies and a diagnosis of PRES was made. The maternal and perinatal outcomes in these women were studiedResults: In the past three years we had 55 cases of eclampsia who underwent neuroimaging studies for persistent neurological symptoms after 24 hours of MgSO4 treatment. Of these women 30 were diagnosed to have PRES. In the present study PRES was common in multiparous women and more in patients with antepartum eclamptic women. Mean age at diagnosis of PRES was 26±5.1 years. Common presenting symptoms were headache (93.3%) and vomiting (53.3%). The mean SBP/DBP was 180/110 mmHg. All patients who had recurrent seizures were controlled with MgSO4 alone. 53.3% of our patients had eclampsia related complications and 36.7% required ICU care. There were 3 maternal deaths (10%). Perinatal mortality was 20%.Conclusions: Neuroimaging in eclamptic patients with persistent neurological symptoms could help in early diagnosis of PRES and multidisciplinary approach in management could contribute significantly in reducing the maternal mortality and morbidity.

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Section: Resultssupporting

confidence: 75%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Maternal and perinatal outcome in eclampsia complicated by posterior reversible encephalopathy syndrome; a three years’ experience in a tertiary care hospital

Karanth

Gonsalves

Sheela

et al. 2017

Int J Reprod Contracept Obstet Gynecol

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“…Also, it was noted that PRES was more common in primigravidas and younger age group patients. 26 Furthermore, PRES and the seizures of eclampsia seem to be pathophysiologically related. 27 Early recognition of PRES is important for proper management and avoidance of complications.…”

Section: Discussionmentioning

confidence: 99%

Neurology Case Studies

Farooq

Gorelick

2016

Neurologic Clinics

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“… 5 Many patients with PRES do not show typical risk factors such as hypertension, eclampsia, immunosuppression or an inflammatory state. 6–10 We present the rare case of a female HIV-infected patient with a long history of antiretroviral treatment (ART), an undetectable HIV viral load and a high CD4 cell count. No classical risk factors for PRES were present.…”

Section: Introductionmentioning

confidence: 99%

Posterior reversible encephalopathy syndrome in an HIV-infected patient on antiretroviral treatment: what is the risk factor?

et al. 2018

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Posterior reversible encephalopathy syndrome (PRES) is a rare but well-described syndrome associated with a high morbidity and a substantial mortality. We present an illustrative case of an HIV-infected but virologically suppressed patient who complained of visual impairment accompanied by severe headache and epileptic seizures. The cerebral CT scan and the follow-up cranial MRI confirmed the diagnosis of PRES. Unlike the cases of HIV-infected patients with PRES published so far, our patient suffered neither from advanced immunodeficiency nor from opportunistic infection or from any other evident predisposing factor. This case highlights that the absence of classical risk factors does not exclude the diagnosis of PRES. We discuss the hypothesis that in accordance with the new pathophysiological theory, persistent HIV-associated cerebrovascular reactivity in combination with endothelial dysfunction may represent an undetected risk factor for the development of PRES in virologically and immunologically stable patients.

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A Study of Eclampsia Cases Associated with Posterior Reversible Encephalopathy Syndrome

Cited by 11 publications

References 14 publications

Maternal and perinatal outcome in eclampsia complicated by posterior reversible encephalopathy syndrome; a three years’ experience in a tertiary care hospital

Maternal and perinatal outcome in eclampsia complicated by posterior reversible encephalopathy syndrome; a three years’ experience in a tertiary care hospital

Neurology Case Studies

Posterior reversible encephalopathy syndrome in an HIV-infected patient on antiretroviral treatment: what is the risk factor?

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