A Study of Criteria for Blood Donor Deferral

Abstract

Donor deferral rates in regional blood centers vary from 5 to 24 per cent, reducing by more than 1,250,000 the number of units of volunteer blood available for transfusion in the nation each year. Those criteria for donor deferral which are intended to exclude donors likely to suffer a "donor reaction" are based partially on untested hypotheses and tradition. In a six-month prospective study, we adopted more liberal criteria for donor acceptance. During this period, donor reaction rates did not increase, and the deferral rate fell from 10 to 7 per cent. Our findings suggest that less restrictive criteria can be used for donor selection without compromising donor safety. If all blood centers reduced their deferral rates to 7 per cent, the nation's blood supply would be increased by more than 500,000 units annually.

Analysis of Donor Deferral in Blood Donors

“…Donor deferral rates in blood canters vary from 5 to 24% leading to huge losses in terms of available units for transfusion in the nation every year. [6] In the present study the overall deferred rate was 4.27% and the deferred rate was higher in males (65.33%) compared to females (34.67%).This was similar to that observed by Unikrishnan B [1] (5.2%), Sundar P [3] (6%), Agnihothri N [5] (11.6%). The higher rate (8-15%) was reported by Chaudhary [7] , Lim [2] , Blumberg [8] , Ranveet.…”

The Incidence of Vaso-vagal Reactions Among Whole Blood Donors During or Immediately After Donation

“…In our study Female donors had a statistically significant higher rate of VVR, which supports findings of previous studies [13][14][15] . On the other hand many other authors reported that there is no significant difference between men and women donors for VVR [16][17][18] . We found that 71.2% of donors suffered with VVR were new donor and 28.8% were repeat donor.…”

Reacciones adversas inmediatas a la donación: frecuencia y caracterización, Banco de Sangre de la Clínica Cardiovascular Santa María, Medellín, 1999

“…Varios autores coinciden en que la edad menor de Diversos factores relacionados con la experiencia 25 a 30 años y la donación por primera vez son de la donación influyen en el retorno de donantes a factores de riesgo para la presencia de efectos indeseables a la donación (1,2,(6)(7)(8). Esta situación podría explicarse porque usualmente la primera donación se efectúa a más temprana edad; además, las personas jóvenes tienen sensibilidad barorreceptora ventncular más baja que los individuos mayores, quienes suelen ser hemodinámicamente más estables (1).…”

“…El sexo femenino fue un factor de predisposición a la reacción vasovagal, a diferencia de lo registrado en otros estudios (1,6,7). Una posible explicación puede ser el peso corporal menor en el sexo femenino con relación al sexo masculino (cuadro l), con la consiguiente hipovolemia, secundaria al mayorvolumen de sangre perdido, en donantes de más baja estatura.…”