A study of chromosomal aberrations in miners exposed to diesel exhausts.

Abstract

NORDENSON I, SWEINS A, DAHLGREN E, BElCNMAN L. A study of chromosomal aberrations in miners exposed to diesel exhausts. Scand j work environ health 7 (1981) 14-17. A study was made of chromosomal aberrations in cultured lymphocytes from a group of 14 miners exposed to diesel exhausts and a reference group of office employees and construction workers. No increased frequency of chromosomal aberrations was observed. The frequency of chromosomal aberrations (both gaps and breaks) W<lS, however, found to be associated with smoking.

Chromosome changes in workers (smokers and nonsmokers) exposed to automobile fuels and exhaust gases.

“…There was however an indication of synergism between smoking and exposure to arsenic (20), and in miners and a reference group there was an increased frequency of both gap3 and breaks among smokers (22). In a study of the frequency of dicentric and ring chromosomes and of chromatid translocations, a higher incidence was found in heavy smokers (40-60 cigarettes/d) than in an undefined reference group (23).…”

Biomarkers of chromosomal damage in peripheral blood lymphocytes induced by polycyclic aromatic hydrocarbons: a meta-analysis

“…7). The study was homogenous for CA (aberrations per 100 cells), while including Bender et al (1988), Heussner et al (1985), Nordenson et al (1981), and Santos-Mello and Cavalcante (1992), the Q value for test of heterogeneity was 6.95 (df = 3, P = 0.07) (Fig. 8).…”

Community and Occupational Studies of Lung Cancer and Polycyclic Organic Matter

“…However, NUMBER miners operating diesel engines did not have increased rates of aberrations when compared with office employees and construction workers (26). Swedish workers handling motor fuels (e.g., road tanker drivers) and industrial workers exposed to benzene had increased frequencies of aberrations, but this was not the case with either ship tanker crews or the staff of the filling stations.…”