A study of cerebellar inositol 1,4,5-trisphosphate receptor following climbing and parallel fibre deafferentation

Li, Peter P.; Green, Marty A.; Warsh, Jerry J.

doi:10.1016/0006-8993(91)90875-v

Cited by 3 publications

(4 citation statements)

References 29 publications

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“…Controlling the polymer membrane configurations in metal battery systems could bring new opportunities which are not viable when using conventional membranes without any specific configuration. Over the few years, several approaches to accentuate the effect of the physical configuration of polymer membranes on dendrite‐suppressing abilities have been suggested including asymmetric, [ 65 ] sandwiched, [ 66 ] and multilayered configurations. [ 67 ] Table 5 summarizes various configurations of polymer materials and their electrochemical properties.…”

Section: Modulating Physical Configuration Of Polymer Membranesmentioning

confidence: 99%

“…Reproduced with permission. [ 66e ] Copyright 2017, Wiley‐VCH GmbH. c) Schematic diagrams for the fabrication process of skeleton materials of composite bio‐based GPE (c‐GPE) (top) and dendrite‐suppressing mechanism with a traditional separator (bottom, left) and c‐GPE (bottom, right).…”

Section: Modulating Physical Configuration Of Polymer Membranesmentioning

confidence: 99%

“…As opposed to the aforementioned asymmetrical geometry, symmetric configurations can also serve as a useful orientation to suppress the dendrite growth. [ 66 ] The symmetric configuration can be readily achieved by sandwiching distinct materials in a sequence of A/B/A, where A and B could be, for example, polymer and ceramic phases, respectively. The sandwich architecture combines the advantages of both polymer and ceramic materials in a single component.…”

Section: Modulating Physical Configuration Of Polymer Membranesmentioning

confidence: 99%

“…have devised a sandwiched tri‐layer separator, where a layer of silica nanoparticles is sandwiched by two symmetric polyolefin separators as illustrated in Figure 7b. [ 66e ] In detail, a layer of silica nanoparticles with a diameter of 400 nm was coated onto a 12 µm thick polyolefin separator using PVDF as a binder. The tri‐layered separator with a thickness of approximately 44 µm was prepared by simply stacking the two identical silica‐coated separators.…”

Section: Modulating Physical Configuration Of Polymer Membranesmentioning

confidence: 99%

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Dendrite‐Suppressing Polymer Materials for Safe Rechargeable Metal Battery Applications: From the Electro‐Chemo‐Mechanical Viewpoint of Macromolecular Design

Kwon

Kim

Shim

2021

Macromol. Rapid Commun.

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Metal batteries have been emerging as next‐generation battery systems by virtue of ultrahigh theoretical specific capacities and low reduction potentials of metallic anodes. However, significant concerns regarding the uncontrolled metallic dendrite growth accompanied by safety hazards and short lifespan have impeded practical applications of metal batteries. Although a great deal of effort has been pursued to highlight the thermodynamic origin of dendrite growth and a variety of experimental methodologies for dendrite suppression, the roles of polymer materials in suppressing the dendrite growth have been underestimated. This review aims to give a state‐of‐the‐art overview of contemporary dendrite‐suppressing polymer materials from the electro‐chemo‐mechanical viewpoint of macromolecular design, including i) homogeneous distribution of metal ion flux, ii) mechanical blocking of metal dendrites, iii) tailoring polymer structures, and iv) modulating the physical configuration of polymer membranes. Judiciously tailoring electro‐chemo‐mechanical properties of polymer materials provides virtually unlimited opportunities to afford safe and high‐performance metal battery systems by resolving problematic dendrite issues. Transforming these rational design strategies into building dendrite‐suppressing polymer materials and exploiting them towards polymer electrolytes, separators, and coating materials hold the key to realizing safe, dendrite‐free, and long‐lasting metal battery systems.

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Section: Modulating Physical Configuration Of Polymer Membranesmentioning

confidence: 99%

Section: Modulating Physical Configuration Of Polymer Membranesmentioning

confidence: 99%

Section: Modulating Physical Configuration Of Polymer Membranesmentioning

confidence: 99%

Section: Modulating Physical Configuration Of Polymer Membranesmentioning

confidence: 99%

See 2 more Smart Citations

Dendrite‐Suppressing Polymer Materials for Safe Rechargeable Metal Battery Applications: From the Electro‐Chemo‐Mechanical Viewpoint of Macromolecular Design

Kwon

Kim

Shim

2021

Macromol. Rapid Commun.

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Inositol 1,4,5-trisphosphate receptor in developing and senescent rat cerebellum

Vecil

Green

et al. 1992

Neurobiology of Aging

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Lithium Modulation of Phosphoinositide Signaling System in Rat Cortex: Selective Effect on Phorbol Ester Binding

Sibony

Green

et al. 1993

Journal of Neurochemistry

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Recent work indicates that the therapeutic action of lithium may be mediated through perturbation of postreceptor second messenger systems. To elucidate further the postreceptor cellular sites of action(s) of lithium, the effect of chronic lithium treatment on various components of the receptor-activated phosphoinositide pathway was investigated. We found that chronic administration of lithium (0.2% LiCl, 21 days) to adult male rats did not significantly affect phosphoinositide hydrolysis in cerebral cortical slices induced by carbachol (1 mM) or NaF (10 mM). Nor did the same treatment alter the carbachol (1 mM) potentiation of guanosine 5'-(gamma-thio)triphosphate (30 microM) stimulation of phosphoinositide hydrolysis (an index of receptor/G protein coupling) in cortical membranes. Immunoblotting studies revealed no changes in the levels of G alpha q/11 immunoreactivity in the cortex after chronic lithium treatment. The levels of protein kinase C, as revealed by specific binding of [3H]phorbol dibutyrate ([3H]PDBu), were significantly reduced in the cytosolic fraction and increased in the particulate fraction of rat cortex after chronic lithium, whereas the KD of [3H]PDBu binding remained relatively constant. A small and insignificant decrease in the density of [3H]inositol 1,4,5-trisphosphate binding was also found in the cortex. The above data suggest that chronic lithium treatment affects neither the muscarinic cholinergic-linked phosphoinositide turnover nor the putative G protein alpha subunit (G alpha q/11) responsible for phospholipase C activation. However, a possible translocation and activation of protein kinase C activity may be significant in the therapeutic effect of this mood-stabilizing agent.

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A study of cerebellar inositol 1,4,5-trisphosphate receptor following climbing and parallel fibre deafferentation

Cited by 3 publications

References 29 publications

Dendrite‐Suppressing Polymer Materials for Safe Rechargeable Metal Battery Applications: From the Electro‐Chemo‐Mechanical Viewpoint of Macromolecular Design

Dendrite‐Suppressing Polymer Materials for Safe Rechargeable Metal Battery Applications: From the Electro‐Chemo‐Mechanical Viewpoint of Macromolecular Design

Inositol 1,4,5-trisphosphate receptor in developing and senescent rat cerebellum

Lithium Modulation of Phosphoinositide Signaling System in Rat Cortex: Selective Effect on Phorbol Ester Binding

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