A Study of CCSVI with Imaging-Blinded Assessment: Neurosonography Update (S10.005)

Clinical Outcomes in Multiple Sclerosis Patients Following Venous Angioplasty

“…Another recent methodologically sound study by Barreto et al found no difference in CCSVI prevalence in MS subjects (n=198) vs. those with other neurological disease or healthy controls. 17 Three recent studies found no differences in CCSVI prevalence in pediatric MS patients vs. healthy controls. Zivadinov et al conclude that these findings point against CCSVI having a primary causative role in MS. [18][19][20] In this issue of the Canadian Journal of Neurological Sciences, Pryse-Phillips et al 1 report the results of a one-year observational study of patients with multiple sclerosis (MS) who underwent venous angioplasty for chronic cerebrospinal venous insufficiency (CCSVI), which has been proposed to be the underlying cause of MS. 2 Subjects who underwent the procedure (n=30) demonstrated a significant improvement in subjective symptomatology one month post-procedure, as measured by the multiple sclerosis impact scale ,which is a patientreported outcome scale.…”