A Study of Association of Sex Hormones With Insulin Resistance and Obesity for Diabetes Mellitus Risk in Adult Women

Abstract

BACKGROUNDSex hormones have a great impact on energy metabolism, body composition, vascular function and inflammatory responses and insulin resistance. Ovarian hormones influence insulin sensitivity across the lifespan of women. DM prevalence also affects women's health across the life stages causing the second highest mortality in South Asians. DM has polyfactorial aetiological differences between males and females. There is need of search of sex/gender specific risk factors of DM in middle aged women. Therefore, this study is undertaken to analyse the association of sex hormones with insulin resistance, obesity and lipid profile thereby to assess the DM risk.