A study of 135 cases of carcinoma in situ of the cervix at the free hospital for women

Some Clinical and Histologic Observations on >>Precanceroses>> of the Portio Vaginalis Uteri

“…The mean age of the patients in the writer's material agrees fairly well with the mean age of 40.8 years reported by PUND et al (15) in 63 patients with so-called »pre-invasive cancer», of 37.7 years by YOUNGE et al (26) in 135 patients with carcinoma in situ, and 39.8 years by Ross and CUYLER (16) in 52 patients with intra-epithelial carcinoma.…”

“…These, it will be realized, will be performed on women mainly in the reproductive age; the mean age of patients with changes in the portio mucosa, as far as can be gathered, is about one decade below the mean age of patients with manifest cancer of the uterine cervix (7,16,26). Even with the present improvements in anaesthetic and operative technic, the operative mortality in total hysterectomy can hardly be expected to be less than about 0.5-1 %; this figure cannot be ignored when, after all, we are concerned with changes the possible malignancy of which is uncertain, or at any rate unclarified.…”

Surgical Approach to Coarctation of the Aorta Complicating Pregnancy

“…This x-ray ( fig. 1 ), in addition to demon¬ strating minimal pneumonic changes in the lower lobe of the right lung, revealed notching along the inferior borders of the 6 ribs and cardiac enlargement to the left, and for the first time we had a clue to the correct diagnosis. A thorough search was then made for physical evidence of coarctation of the aorta, and all the classical signs were found.…”

Biobanking and public health: is a human rights approach the tie that binds?

“…2000). For example, the Pap smear would not have been developed (Younge et al 1949) and the nonsteroidal estrogen hormone, diethylstilbestrol (DES), would not have been found to be carcinogenic (Herbst 1981). Without the knowledge gained from autopsies of Korean War veterans, science would have known less about the age of onset for atherosclerosis (Enos et al 1955).…”