1962
DOI: 10.1099/00221287-28-4-571
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A Study by Fluorescence Microscopy of the Replication of Inclusion Blennorrhoea Virus in HeLa Cell Monolayers

Abstract: SUMMARYThe infectious agent of inclusion blennorrhoea was seen by fluorescence microscopy as a particle of deoxyribonucleic acid (DNA) 0.2 p diam.These infectious particles and particles inactivated at 4" and 56" were adsorbed by HeLa cell monolayers. The inactivated particles were visible for at least 6 hr., distributed at random on the cells, while the infectious particles rapidly disappeared. Multiple infections of the cells readily occurred and in cells so infected, a cluster of ribonucleic acid (RNA) part… Show more

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Cited by 7 publications
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