A Study about Demographic, Clinical, Comorbidity and lipid profile of hypothyroid patients attending a tertiary health care institute of Rajasthan

Mathur, Medha

doi:10.18535/jmscr/v6i8.91

Cited by 3 publications

(4 citation statements)

References 7 publications

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“…[44] In the current study, overall prevalence of SCHypo is found to be 33.75%, which coincides with many studies. [29,36,45,46] In our study, SCHypo was common in the age group of 60-79 (57.6%, 109/189). Similar observations were reported in few studies [20,35] few studies reported lower age groups in this context.…”

Section: Discussionsupporting

confidence: 51%

“…[27][28][29][31][32][33][34][35] Results of current study as well as previous studies support the fact that hypothyroidism is more common in females. [36] In most of studies the thyroid disorders were common in the age group between 20 and 45, [37,38] but we observed a higher proportion within 50-79. This variation may be due to the fact that we have included only those subjects who underwent CABG, which is more pervasive in higher age groups.…”

Section: Discussionmentioning

confidence: 47%

“…This was a very common observation which was noted by a number of studies, for instance a study from Andhra Pradesh, [47] showed 86.53% of SCHypo and 13.46% OVHypo. [25,27,29,36,45,48] Our overall prevalence for OVHypo was found to be 2.3% and its proportion among the other thyroid disorders is 5.6%. Some recent studies had similar observations.…”

Section: Discussionmentioning

confidence: 64%

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How widespread is Thyroid Disorders among Patients undergoing Coronary Artery Bypass Grafting? A Study from Tertiary Care Hospital

Kahol¹,

Kathait²,

Mishra³

et al. 2022

APJHS

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Coronary artery bypass grafting (CABG) is the most commonly performed cardiac procedure and thyroid disorders (hypothyroidism and hyperthyroidism) are the most widespread endocrine diseases. Till date, there is no Indian study pertaining to prevalence of thyroid disorders among subjects undergoing CABG. The aim of this study was to determine the prevalence of thyroid disorders among subjects undergoing CABG in a tertiary care hospital. This is a prospective observational hospital-based study having 560 subjects who underwent CABG. Pre-operative thyroid tests were conducted of all the subjects. On the basis of this test, subjects were divided into groups, “Euthyroid” (normal thyroid status) and Thyroid subjects, that is, Subclinical Hypothyroidism (SCHypo), Overt Hypothyroidism (OVHypo), Subclinical Hyperthyroidism (SCHyper), and Overt Hyperthyroidism (OVHyper), based on thyroid function test. The proportion of the disorders was calculated. The study population included 560 subjects (Males: 457 females: 103). The overall prevalence of thyroid function abnormalities was 41.07%. The SCHypo was the most pervasive thyroid disorder (33.75%), followed by SCHyper (4.28%), OVHypo (2.32%), and OVHyper (0.7%). Highest number of thyroid subject (57.8%) was in 40–59 age group and lowest (0.86%) in 18–39. Thyroid was more prevalent among females (45/103) than in males (185/457). Among subjects undergoing CABG, SCHypo was most common followed by SCHyper, OVHypo, and OVHyper. Among the subjects undergoing CABG, maximum thyroid cases are in the age group of 60–79 with female preponderance.

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Section: Discussionsupporting

confidence: 51%

Section: Discussionmentioning

confidence: 47%

Section: Discussionmentioning

confidence: 64%

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How widespread is Thyroid Disorders among Patients undergoing Coronary Artery Bypass Grafting? A Study from Tertiary Care Hospital

Kahol¹,

Kathait²,

Mishra³

et al. 2022

APJHS

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“…The goal of the study is to clarify these links in order to improve patient care for patients with thyroid dysfunction as well as clinical practices and treatment techniques. [13,14,15]…”

Section: Introductionmentioning

confidence: 99%

An observational study on assessment of thyroiddysfunction and its co-existing conditions in a government area hospital

2024

Int. J. Adv. Res. Biol. Sci

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Introduction: Healthcare professionals have a great deal of difficulty when thyroid dysfunction coexists with other medical disorders, making diagnosis and treatment more difficult. Thyroid dysfunction is frequently accompanied withconditions such as cardiovascular illnesses, diabetes mellitus, and autoimmune disorders, which can exacerbatepatient morbidity and affect treatment results overall. Comprehensive patient management requires an understandingof the relationships between comorbid diseases and thyroid dysfunction. The objective of this study is to improvetreatment practices and further our understanding of the intricate interactions between thyroid dysfunction andcomorbid illnesses by examining the incidence of thyroid dysfunction in a hospital context. In the end, our researchaims to ensure comprehensive and successful treatment options for individuals with thyroid dysfunction, improvingtheir management and care. Methods and Material: This was a observational study conducted in a Government area hospital in the duration of 6 months. In this study wecollected demographic details, past medical and medication history, current therapy and respective laboratory datai.e., thyroid profile of a patient. The associated co-existing conditions were studied and evaluated using SPSSsoftware Results: This study demonstrates that maximum number of patients suffering with thyroid disorders are females. Age group of 31-40 male are more likely suffering from thyroid disorder. Most of the people are suffering from hypothyroidism. People who are using levothyroxine 50 mcg are more when compared with other doses and people using bothcarbimazole and methimazole are same. People suffering from CVS are more than other co-morbidities.In aspect of both hypothyroidism and hyperthyroidism, females are more prone to CVS compared to malesConclusion: The study's combined data demonstrated that, in comparison to hyperthyroidism, more occurrences of hypothyroidism were observed in females than in males. Although the entire sample size indicates that females aremore susceptible to thyroid problems, men (38%) and females (27%) of the same age are more impacted by thyroidabnormalities. As per the comorbidities mentioned in our study, CVS accounts for 24%, with DM (12%), CNS (6%), ortho (5%), toxicity (4%) and other comorbidities following closely after. Relevant cardiovascular issues arise fromeither increased or decreased thyroid hormone activity on certain molecular pathways in the heart and vasculature Keywords: Thyroid Disorders, Hypothyroid, Hyperthyroid, Comorbidities

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Correlation of Hypothyroidism with Age and Comorbidities Among Women: A Cross-Sectional Study

Ifthikhar,

Dhamotharaswamy

2024

Journal of Pharmacology and Pharmacotherapeutics

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Background Hypothyroidism, an endocrine disorder caused by thyroid dysfunction found to be more prevalent globally in females than in males. Young females are more prone to subclinical hypothyroidism (SCH). The study aimed to estimate the different types of hypothyroidism based on the clinical profile of thyroid hormone and to detect various comorbidities in correlation with age in women. In female patients with hypothyroidism, there is a significant association between age groups and the type of hypothyroidism (subclinical, clinical, overt), with younger age groups showing a higher prevalence of SCH. Additionally, comorbidities, such as polycystic ovarian disorder (PCOD), are more prevalent in hypothyroidism patients, particularly in those with SCH. Materials and Methods A prospective cross-sectional study executed in a tertiary care hospital for one year with an inclusion of female hypothyroid patients above 18 years of age. An informed written consent form was received from each patient with clarification of the protocol. Results A total of 44.6% women were in the 18–28 years of age group (young females) and 42.8% of women with SCH. PCOD (38.2%) was a predominant comorbid condition among hypothyroidism women. In the age group of 18–28 years, there were significantly more patients 114 (81.4%) with SCH ( p < 0.01) than those with clinical 22 (18.4%) and overt hypothyroidism 10 (14.7%). The hypothyroidism of women with PCOD 95 (67.8%) was significantly ( p < 0.01) more in subclinical than clinical 28 (23.5%) and overt hypothyroidism 2 (2.9%). Conclusion Thyroid dysfunction is uncertain in females, bulges to complications of maternal and fetal outcomes, and is associated with other comorbidities, leading to an increase in the mortality rate. Hypothyroidism is a growing burden for other comorbidities. Pharmaceutical care by healthcare professionals is to be adopted with prompt diagnostic and screening techniques.

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A Study about Demographic, Clinical, Comorbidity and lipid profile of hypothyroid patients attending a tertiary health care institute of Rajasthan

Cited by 3 publications

References 7 publications

How widespread is Thyroid Disorders among Patients undergoing Coronary Artery Bypass Grafting? A Study from Tertiary Care Hospital

How widespread is Thyroid Disorders among Patients undergoing Coronary Artery Bypass Grafting? A Study from Tertiary Care Hospital

An observational study on assessment of thyroiddysfunction and its co-existing conditions in a government area hospital

Correlation of Hypothyroidism with Age and Comorbidities Among Women: A Cross-Sectional Study

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