A Structured Assessment Protocol for Children With Acquired Brain Injuries in an Inpatient Rehabilitation Hospital

Uses of the NIH Toolbox® in Clinical Samples

“…Finally, although we sought to identify records using the NIH Toolbox in clinical research, we identified 6 records reporting applications of NIH Toolbox measures in clinical settings (e.g., inpatient and outpatient medical clinics) for clinical purposes (e.g., to inform clinical practice and/or as part of routine care). These records demonstrated that the NIH Toolbox is feasible for use at rehabilitation settings with a pediatric brain injury population, [11][12][13] is minimally disruptive to the clinical operations of a multidisciplinary outpatient gastroenterology clinic, 16 is valid for use among older adults at different stages of cognitive health at a memory clinic, 15 and can serve as a rapid screening tool in the outpatient setting to identify patients at a high risk for severe encephalopathy. 14 These findings underscore the great potential of the NIH Toolbox for use in routine clinical practice.…”

“…[11][12][13] These 3 records concluded that the NIH Toolbox Cognition Battery was a practical tool for tracking cognitive function among patients undergoing active treatment and those in rehabilitation because of the low patient burden and easy fit into the standard clinical workflow. [11][12][13] Of these, one record further reported successfully incorporating NIH Toolbox data into individualized clinical treatment plans. 12 The NIH Toolbox Cognition Battery has also been used as a diagnostic tool in a memory clinic to discriminate older adults with varying levels of cognitive impairment 15 and as a rapid cognitive screening tool in routine outpatient care to assess cognitive functioning among ambulatory patients with advanced liver disease.…”

“…[11][12][13] Of these, one record further reported successfully incorporating NIH Toolbox data into individualized clinical treatment plans. 12 The NIH Toolbox Cognition Battery has also been used as a diagnostic tool in a memory clinic to discriminate older adults with varying levels of cognitive impairment 15 and as a rapid cognitive screening tool in routine outpatient care to assess cognitive functioning among ambulatory patients with advanced liver disease. 14 Finally, the NIH Toolbox Cognition Battery has been used in a gastroenterology clinic to monitor treatment response in a case study that assessed the effect of a gluten-free diet on celiac disease.…”

“…The other category (n = 40, 14.2%) contained a variety of clinical diagnoses, While most records reported applications of the NIH Toolbox in research with clinical samples, 6 reported implementation in clinical settings. [11][12][13][14][15][16] Specifically, applications of NIH Toolbox Cognition Battery measures were reported among pediatric patients with brain tumors in both perioperative and follow-up inpatient and day treatment rehabilitation settings, [11][12][13] patients living with liver cirrhosis in an outpatient transplant clinic, 14 patients with dementia at a memory clinic, 15 and patients with celiac disease at a multidisciplinary outpatient gastroenterology clinic. 16 Study Design An observational study design was used in 39.9% (n = 112) of included records, compared with an experimental study design in 60.1% (n = 169).…”

“…In particular, 3 records assessed the feasibility of administering the NIH Toolbox Cognition Battery to pediatric patients who had sustained acquired brain injuries as primary outcome measures. [11][12][13] These 3 records concluded that the NIH Toolbox Cognition Battery was a practical tool for tracking cognitive function among patients undergoing active treatment and those in rehabilitation because of the low patient burden and easy fit into the standard clinical workflow. [11][12][13] Of these, one record further reported successfully incorporating NIH Toolbox data into individualized clinical treatment plans.…”