2022
DOI: 10.1007/s13738-022-02522-x
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A structural and optical study of curcumin and curcumin analogs

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Cited by 8 publications
(6 citation statements)
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“…First, we introduced succinic anhydride into the end of curcumin through esterification to obtain curcumin succinate (Figure S1). From the NMR and FTIR spectra (Figures S2–S5), the curcumin succinate has been successfully prepared. , Subsequently, through theoretical calculation and experimental studies, we found that succinic anhydride modification at the end of curcumin (red labeled-COOH) can form an IL with betaine (blue labeled-COO – ) by hydrogen bond interaction (Figure a). Both the ESP (Figure b) and the RDG (Figure c) diagrams showed that curcumin succinate and betaine can successfully prepare Cur-Bet-IL through hydrogen force interconnection. , This IL not only has good fluidity and stability at room temperature but also maintains the biological activity of curcumin (Figure S6).…”
Section: Resultsmentioning
confidence: 99%
“…First, we introduced succinic anhydride into the end of curcumin through esterification to obtain curcumin succinate (Figure S1). From the NMR and FTIR spectra (Figures S2–S5), the curcumin succinate has been successfully prepared. , Subsequently, through theoretical calculation and experimental studies, we found that succinic anhydride modification at the end of curcumin (red labeled-COOH) can form an IL with betaine (blue labeled-COO – ) by hydrogen bond interaction (Figure a). Both the ESP (Figure b) and the RDG (Figure c) diagrams showed that curcumin succinate and betaine can successfully prepare Cur-Bet-IL through hydrogen force interconnection. , This IL not only has good fluidity and stability at room temperature but also maintains the biological activity of curcumin (Figure S6).…”
Section: Resultsmentioning
confidence: 99%
“…These isomers have slightly different chemical properties and biological activities and coexist in turmeric extracts [20]. While curcumin is the most researched and commonly known isomer, both dimethoxy-curcumin and bis-dimethoxy-curcumin also contribute to the overall biological effects of turmeric and its derived products [21]. The presence of these isomers may influence the overall health benefits and bioactivities attributed to turmeric or curcumin supplements.…”
Section: Curcumin's Chemical Propertiesmentioning
confidence: 99%
“…Curcumin (CUR, C 21 H 20 O 6 , CAS registry No. 458-37-7) is a typical organic small molecule with intramolecular hydrogen bonding of enol isomerization and both keto-enol and β-diketone (Scheme ) structures. , In solution, the conversion of the keto-enol molecule of curcumin to the β-diketone form can be achieved by adjusting the pH and polarity of the solvent. However, limited by the high energy or fugacity of the β-diketone structure, curcumin is dominated by the keto-enol structure in the solid state . In particular, curcumin in the solid state (crystalline, powder, polymorph, etc.)…”
Section: Introductionmentioning
confidence: 99%