A stretchable and screen-printed electrochemical sensor for glucose determination in human perspiration

Abellán-Llobregat, Alejandra; Jeerapan, Itthipon; Bandodkar, Amay J.; Vidal, Lorena; Canals, Antonio; Wang, Joe; Morallón, Emilia

doi:10.1016/j.bios.2017.01.058

Cited by 290 publications

(162 citation statements)

References 32 publications

Supporting

Mentioning

161

Contrasting

Order By: Relevance

“…5 min) between the point of sweat emergence at the skin surface, to detection by ISE‐RE. Interest in sweat as a means for obtaining personal biochemical via non‐invasive sampling continues to gain interest . A key emerging issue is how to ensure sampling integrity is maintained during a monitoring period.…”

Section: Discussionmentioning

confidence: 99%

Wearable Platform for Real‐time Monitoring of Sodium in Sweat

et al. 2018

View full text Add to dashboard Cite

A fully integrated and wearable platform for harvesting and analysing sweat sodium concentration in real time during exercise has been developed and tested. The platform was largely produced using 3D printing, which greatly simplifies fabrication and operation compared to previous versions generated with traditional production techniques. The 3D printed platform doubles the capacity of the sample storage reservoir to about 1.3 ml, reduces the assembly time and provides simple and precise component alignment and contact of the integrated solid-state ion-selective and reference electrodes with the sorbent material. The sampling flowrate in the device can be controlled by introducing threads to enhance wicking of sweat from the skin, across the electrodes to the storage area. The platform was characterised in the lab and in exercise trials over a period of about 60 minutes continuous monitoring. Sweat sodium concentration was found to rise initially to approximately 17 mM and decline gradually over the period of the trial to about 11-12 mM.

show abstract

Section: Discussionmentioning

confidence: 99%

Wearable Platform for Real‐time Monitoring of Sodium in Sweat

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Prussian Blue screen-printed electrodes (PB-SPEs) were modified following a modified version of a previously reported protocol. [39] Briefly, 4 µL of a 0.5% wt. chitosan solution prepared in 0.1 M acetic acid was cast on the surface of the electrodes and allowed to dry at room temperature.…”

Section: Glucose Biosensor Fabricationmentioning

confidence: 99%

Electrochromic biosensors based on screen-printed Prussian Blue electrodes

Pellitero

Fremeau

Villa

et al. 2019

Sensors and Actuators B: Chemical

View full text Add to dashboard Cite

Highlights We present the production of an electrochromic screen-printable paste based on Prussian Blue. These blue electrodes display excellent spectroelectrochemical reversibility and high catalytic activity towards the reduction of H2O2.  These blue electrodes enable both the electrochemical and optical quantitative determination of hydrogen peroxide.  The reported blue electrodes are highly suitable transducers for the construction of oxidase-based biosensors.  A glucose biosensor is presented to demonstrate the spectroelectrochemical capabilities of these new electrodes. AbstractPrussian Blue (PB)-modified graphite screen-printed electrodes are increasingly being used in electrochemical biosensors. However, they do not allow the observation of the electrochromism of PB. This work presents the construction of PB-based, electrochromic screen-printed biosensors. Although electrically more resistive than their graphite counterparts, these new PBbased electrodes enable both the amperometric and colorimetric detection of hydrogen peroxide.This is the first time that this has been achieved using screen-printed electrodes, and we demonstrate it spectroelectrochemically on a glucose biosensor. The biosensor electrochemical performance equals that of previously reported PB/graphite electrodes, being able to detect down to 4 µM H2O2 and 54 µM glucose. At the same time, and in contrast to PB/graphite electrodes, the new PB-based electrodes afford the optical detection of these two analytes down to 1.2 µM and 15 µM, respectively. The dynamic ranges of the glucose biosensors obtained at the PBbased electrodes are 0.1-1 mM (amperometric) and 0.025-2.5 mM (Colorimetric), matching the physiological glucose concentration range in body fluids other than blood or serum.

show abstract

“…This method was successfully applied to stretchable biosensors for perspiration glucose, ethanol, caffeine, etc. with potentials in both healthcare and chemically sensitive robotic skin …”

Section: Flexible and Patchable Biosensors For Cyber Biochemical Intementioning

confidence: 99%

“…with potentials in both healthcare and chemically sensitive robotic skin. [204,205] On the other hand, as the reference electrode (RF) potential is highly dependent on chloride concentration, to avoid potential shift, an optimized salt bridge has been proposed to minimize equilibration between RF and the solutions. [206] Taking the advantages of salt bridge, reliable Cl − testing (<40 × 10 −3 m) during 1 h continuous exercise was realized compare to rapid increase in Cl − detected by traditional devices without using a salt bridge.…”

Section: Target Detectionmentioning

confidence: 99%

Cyber–Physiochemical Interfaces

et al. 2020

View full text Add to dashboard Cite

Living things rely on various physical, chemical, and biological interfaces, e.g., somatosensation, olfactory/gustatory perception, and nervous system response. They help organisms to perceive the world, adapt to their surroundings, and maintain internal and external balance. Interfacial information exchanges are complicated but efficient, delicate but precise, and multimodal but unisonous, which has driven researchers to study the science of such interfaces and develop techniques with potential applications in health monitoring, smart robotics, future wearable devices, and cyber physical/human systems. To understand better the issues in these interfaces, a cyber–physiochemical interface (CPI) that is capable of extracting biophysical and biochemical signals, and closely relating them to electronic, communication, and computing technology, to provide the core for aforementioned applications, is proposed. The scientific and technical progress in CPI is summarized, and the challenges to and strategies for building stable interfaces, including materials, sensor development, system integration, and data processing techniques are discussed. It is hoped that this will result in an unprecedented multi‐disciplinary network of scientific collaboration in CPI to explore much uncharted territory for progress, providing technical inspiration—to the development of the next‐generation personal healthcare technology, smart sports‐technology, adaptive prosthetics and augmentation of human capability, etc.

show abstract

A stretchable and screen-printed electrochemical sensor for glucose determination in human perspiration

Cited by 290 publications

References 32 publications

Wearable Platform for Real‐time Monitoring of Sodium in Sweat

Wearable Platform for Real‐time Monitoring of Sodium in Sweat

Electrochromic biosensors based on screen-printed Prussian Blue electrodes

Cyber–Physiochemical Interfaces

Contact Info

Product

Resources

About