A strawberry-like Ag-decorated barium titanate enhances piezoelectric and antibacterial activities of polymer scaffold

Shuai, Cijun; Li, Guofeng; Qi, Fangwei; Peng, Shuping; Yang, Wenjing; He, Chongxian; Wang, Guoyong; Qian, Guowen

doi:10.1016/j.nanoen.2020.104825

Cited by 279 publications

(153 citation statements)

References 60 publications

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“…However, limitations of in vitro study have to be taken into account; so far, the effect of roots, soft-tissue, orthodontic force, and jaw movement were not considered. Recently, there have been some studies focused on periodontal inflammation control or bone defects treatment during orthodontic treatment [ 39 , 40 ], suggesting that further research with different simulation design, especially about periodontal tissue and bone tissue changed caused by tooth movement, is necessary. Besides, while the artificial bone used in the present study was well manufactured for focusing on the effects and allowing us to investigate with standardized models where results would be consistent, it would not be identical to the natural bone in terms of chemical composition and physical integrity, especially the biological response to torque and thermal changes.…”

Section: Discussionmentioning

confidence: 99%

Primary Stability of Orthodontic Titanium Miniscrews due to Cortical Bone Density and Re-Insertion

et al. 2020

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The increasing demand for orthodontic treatment over recent years has led to a growing need for the retrieval and reuse of titanium-based miniscrews to reduce the cost of treatment, especially in patients with early treatment failure due to insufficient primary stability. This in vitro study aimed to evaluate differences in the primary stability between initially inserted and re-inserted miniscrews within different cortical bone densities. Artificial bone was used to simulate cortical bone of different densities, namely 20, 30, 40, and 50 pound per cubic foot (pcf), where primary stability was evaluated based on maximum insertion torque (MIT), maximum removal torque (MRT), horizontal resistance, and micromotion. Scanning electron microscopy was used to evaluate morphological changes in the retrieved miniscrews. The MIT, MRT, horizontal resistance, and micromotion was better in samples with higher cortical bone density, thereby indicating better primary stability (P < 0.05). Furthermore, a significant reduction of MIT, MRT, and horizontal resistance was observed during re-insertion compared with the initial insertion, especially in the higher density cortical bone groups. However, there was no significant change in micromotion. While higher cortical bone density led to better primary stability, it also caused more abrasion to the miniscrews, thereby decreasing the primary stability during re-insertion.

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Section: Discussionmentioning

confidence: 99%

Primary Stability of Orthodontic Titanium Miniscrews due to Cortical Bone Density and Re-Insertion

et al. 2020

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“…In vitro biological properties mainly include cytocompatibility, bioactivity, biodegradability, antibacterial activity and so on. Presently, many studies have proved that the incorporation of bioceramics into biomedical metals had a positive effect on cell behavior [172,173]. For example, Guzman et al [38] fabricated Al 2 O 3 -Ti biocermets and analyzed the response of pre-osteoblast cells to the biocermets, as shown in Fig.…”

Section: Biological Properties Of Biocermetsmentioning

confidence: 99%

Advances in biocermets for bone implant applications

et al. 2020

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As two promising biomaterials for bone implants, biomedical metals have favorable mechanical properties and good machinability but lack of bioactivity; while bioceramics are known for good biocompatibility or even bioactivity but limited by their high brittleness. Biocermets, a kind of composites composing of bioceramics and biomedical metals, have been developed as an effective solution by combining their complementary advantages. This paper focused on the recently studied biocermets for bone implant applications. Concretely, biocermets were divided into ceramic-based biocermets and metal-based biocermets according to the phase percentages. Their characteristics were systematically summarized, and the fabrication methods for biocermets were reviewed and compared. Emphases were put on the interactions between bioceramics and biomedical metals, as well as the performance improvement mechanisms. More importantly, the main methods for the interfacial reinforcing were summarized, and the corresponding interfacial reinforcing mechanisms were discussed. In addition, the in vitro and in vivo biological performances of biocermets were also reviewed. Finally, future research directions were proposed on the advancement in component design, interfacial reinforcing and forming mechanisms for the fabrication of high-performance biocermets.

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“…While these methods may require more complex conditions and are difficult to control. Blending other biodegradable polymers with fast degradation rate has been widely used as a simple and effective way to improve the degradation rate [ 19 , 20 ]. Among the biodegradable polymers, poly (glycolic acid) (PGA) is a FDA-approved polymer with a relatively fast degradation rate [ 21 ].…”

Section: Introductionmentioning

confidence: 99%

Accelerated degradation of HAP/PLLA bone scaffold by PGA blending facilitates bioactivity and osteoconductivity

Shuai

Yang

Feng

et al. 2021

Bioactive Materials

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The incorporation of hydroxyapatite (HAP) into poly- l -lactic acid (PLLA) matrix serving as bone scaffold is expected to exhibit bioactivity and osteoconductivity to those of the living bone. While too low degradation rate of HAP/PLLA scaffold hinders the activity because the embedded HAP in the PLLA matrix is difficult to contact and exchange ions with body fluid. In this study, biodegradable polymer poly (glycolic acid) (PGA) was blended into the HAP/PLLA scaffold fabricated by laser 3D printing to accelerate the degradation. The results indicated that the incorporation of PGA enhanced the degradation rate of scaffold as indicated by the weight loss increasing from 3.3% to 25.0% after immersion for 28 days, owing to the degradation of high hydrophilic PGA and the subsequent accelerated hydrolysis of PLLA chains. Moreover, a lot of pores produced by the degradation of the scaffold promoted the exposure of HAP from the matrix, which not only activated the deposition of bone like apatite on scaffold but also accelerated apatite growth. Cytocompatibility tests exhibited a good osteoblast adhesion, spreading and proliferation, suggesting the scaffold provided a suitable environment for cell cultivation. Furthermore, the scaffold displayed excellent bone defect repair capacity with the formation of abundant new bone tissue and blood vessel tissue, and both ends of defect region were bridged after 8 weeks of implantation.

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A strawberry-like Ag-decorated barium titanate enhances piezoelectric and antibacterial activities of polymer scaffold

Cited by 279 publications

References 60 publications

Primary Stability of Orthodontic Titanium Miniscrews due to Cortical Bone Density and Re-Insertion

Primary Stability of Orthodontic Titanium Miniscrews due to Cortical Bone Density and Re-Insertion

Advances in biocermets for bone implant applications

Accelerated degradation of HAP/PLLA bone scaffold by PGA blending facilitates bioactivity and osteoconductivity

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