A step towards a new targeted nanotherapy for pancreatic cancer

Keen, Judith C.

doi:10.4161/cbt.7.10.6758

Cited by 3 publications

(2 citation statements)

References 15 publications

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“…Nanoparticle albumin bound paclitaxel are designed to deliver insoluble drug to the site of tumor. Liposomal-based nanoparticles are used to encapsulate Irinotecan which increases the efficacy of drug delivery [16]. Ultrasound-responsive nanoparticles are used in ultrasound mediated drug delivery were the nanoparticles are accumulated at the site of tumor via enhanced permeability and retention (EPR) effect and release the encapsulated drug in response to ultrasound.…”

Section: Pancreatic Ductal Adenocarcinoma (Pda)mentioning

confidence: 99%

Nano World in Cancer Therapy

latha¹

2020

Asian Pac J Cancer Biol

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Despite of several pandemic eruptions, cancer still remains the leading cause of death at constant rate. The risk of every alternative disease or disorder increases with the initial incidence of cancer. Cancer treatment has radically changed a lot from conventional therapies like surgery and radiotherapy to targeted therapies like thermal ablation and gene therapy. Deeper knowledge and understanding of key regulators of cancer growth and progression aided in the advancement of cancer therapy. The use of nanoparticles in cancer diagnosis and treatment has gained its importance in the next generation of cancer treatments. Nano oncology enhances the efficacy of chemotherapy for a wide gamut of invasive cancers. Here we provide an overview on the different approaches to treat cancer and discuss the pivotal role of some archetypal cancer therapies and current state and future prospects of diverse biomedical nanomaterials for cancer therapy and imaging.

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Section: Pancreatic Ductal Adenocarcinoma (Pda)mentioning

confidence: 99%

Nano World in Cancer Therapy

latha¹

2020

Asian Pac J Cancer Biol

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“…Dalam segi formulasi telah dikembangkan metode nanomedicine yang dapat menargetkan obat ke sel tumor secara spesifik (Keen, 2008). Formulasi partikel nano dapat meningkatkan ketersediaan hayati dari obat yang larut dalam air yang buruk dengan mengatasi pembubaran obat dan / atau permeabilitas.…”

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Formulasi Nanopartikel Tanaman Herbal Untuk Terapi Kanker

Masitoh

Sopyan²

2019

Maj. Farmasetika

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Kanker termasuk masaalah kesehatan utama di Dunia dan termasuk penyebab kematian nomor dua setelah kardiovaskular. Obat herbal saat ini banyak digunakan untuk pengobatan kanker karena kelimpahan senyawa kimianya yang berpotensi sebagai anti-kanker. Namun tanaman herbal kebanyakan sediaannya kurang larut air dan memiliki bioavailabilitas yang kurang baik. Sehingga perlu dilakukan modifikasi secara fisik ataupun kimia untuk meningkatkan kelarutannya. Salahsatu modifikasi secara fisik yaitu dari segi Formulasi. Nanopartikel adalah salah satu formulasi yang dapat mengatasi masalah-masalah tersebut karena Nanopartikel mampu memperbaiki kelarutan obat herbal dan dapat masuk dan menargetkan sel kanker secara spesifik.Kata kunci : kanker, nanopartikel, tanaman herbal

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