“…We have previously suggested (23,30) that experimental data for processive enzymes may be analyzed by a reaction scheme (Scheme 1), according to which the free enzyme, E, combines with a cellulose strand, C m , to form an activated complex, EC m . The enzyme subsequently moves along the strand, which is sequentially shortened by one cellobiose, moiety C, for each step (so the strand is converted to C m-1 , C m-2 , etc.).…”