“…Such goal can be achieved through the separating hyperplanes generated by supervised statistical learning methods like Perceptron, SVM and LDA [32,14,13]. In the recent years, these methods have played an important role for characterizing differences between a reference group of patterns using image samples of patients [24,26,27,28,12] as well as face images [5,19,25,21]. Besides, their extensions for the non-linear case, as well as the Maximum uncertainty LDA (MLDA) approach to address the limited sample size problem, have been reported in a number of works in the literature [32,14,13,12,24,19,31,26,28,18].…”