A State-of-the-Art Review of Mixing in Microfluidic Mixers

Mansur, Elmabruk A.; Ye, Mingxing; Wang, Yundong; Dai, Yiyang

doi:10.1016/s1004-9541(08)60114-7

Cited by 171 publications

(104 citation statements)

References 101 publications

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“…28 These microfluidic devices have been shown to enhance product selectivity, reaction yields, as well as making considerable steps in the field of reaction optimisation and automation. 29 Microfluidic reactors which flow reactants across 2-dimensional channels networks are typically known as chip reactors or "lab on a chip". The applicability of different microreactors are defined by their size and internal channel designs, the material from which they are manufactured, and also the type of reaction medium/solvent system required.…”

Section: Microfluidic Technologymentioning

confidence: 99%

“…These types of mixers are often a cost-efficient way of inducing efficient mixing into a laminar flow regime. Although a wide range of novel mixing strategies have been demonstrated, generally passive mixers can be classified as being either T or Y shape mixers, 29 serial or parallel lamination, 74 hydrodynamic focussing of mixing streams, 75 the introduction of bubbles of gas 76 or liquid 77 into the flow, or enhanced chaotic advection using patterned channel walls. 78…”

Section: Passive Mixingmentioning

confidence: 99%

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Design and additive manufacture for flow chemistry

et al. 2013

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Section: Microfluidic Technologymentioning

confidence: 99%

Section: Passive Mixingmentioning

confidence: 99%

Design and additive manufacture for flow chemistry

et al. 2013

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“…For example, in one dimension, let us consider the coordinate x = x 0 that corresponds to the interface that separates large physical scales in space and time l s (x) = L s and t s (x) = T s for x ≥ x 0 + x/2 from the small ones l s (x) = l s and t s (x) = t s for x < x 0 − x/2. Then the following space-time transformation rule is considered: 8) and the TARDIS algorithm solves the governing equations in the transformed space-time variablesx andt. By using the scale-adjustable zoom-in function (…”

Section: Microscopic Fluctuations In Liquids (A) Fluctuating Hydrodynmentioning

confidence: 99%

Concurrent multiscale modelling of atomistic and hydrodynamic processes in liquids

Markesteijn

Karabasov

Scukins

et al. 2014

Phil. Trans. R. Soc. A.

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One contribution of 13 to a Theme Issue 'Multi-scale systems in fluids and soft matter: approaches, numerics and applications' . Fluctuations of liquids at the scales where the hydrodynamic and atomistic descriptions overlap are considered. The importance of these fluctuations for atomistic motions is discussed and examples of their accurate modelling with a multi-spacetime-scale fluctuating hydrodynamics scheme are provided. To resolve microscopic details of liquid systems, including biomolecular solutions, together with macroscopic fluctuations in space-time, a novel hybrid atomistic-fluctuating hydrodynamics approach is introduced. For a smooth transition between the atomistic and continuum representations, an analogy with two-phase hydrodynamics is used that leads to a strict preservation of macroscopic mass and momentum conservation laws. Examples of numerical implementation of the new hybrid approach for the multiscale simulation of liquid argon in equilibrium conditions are provided.

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“…curved sections, backward or forward facing steps). Several comprehensive reviews of μ-mixing devices and their principles can be found in the relevant literature [1][2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Design of a Novel <em>μ</em>-Mixer

Kanaris¹,

Mouza²

2017

Preprint

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Abstract:In this work the efficiency of a new μ-mixer design is investigated. As in this type of devices the Reynolds number is low, mixing is diffusion dominated and it can be enhanced by creating secondary flows. In this study we propose the introduction of helical inserts into a straight tube to create swirling flow. The influence of the insert's geometrical parameters (pitch and length of the propeller blades) and of the Reynolds number on the mixing efficiency and on the pressure drop are numerically investigated. The mixing efficiency of the device is assessed by calculating a number, i.e. the Index of Mixing Efficiency that quantifies the uniformity of concentration at the outlet of the device. The influence of the design parameters on the mixing efficiency is assessed by performing a series of "computational" experiments, in which the values of the parameter are selected using DOE methodology. Finally using the numerical data, appropriate design equations are formulated, which, for given values of the design parameters, can estimate with reasonable accuracy both the mixing efficiency and the pressure drop of the proposed mixing device.

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A State-of-the-Art Review of Mixing in Microfluidic Mixers

Cited by 171 publications

References 101 publications

Design and additive manufacture for flow chemistry

Design and additive manufacture for flow chemistry

Concurrent multiscale modelling of atomistic and hydrodynamic processes in liquids

Design of a Novel <em>μ</em>-Mixer

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A State-of-the-Art Review of Mixing in Microfluidic Mixers

Cited by 171 publications

References 101 publications

Design and additive manufacture for flow chemistry

Design and additive manufacture for flow chemistry

Concurrent multiscale modelling of atomistic and hydrodynamic processes in liquids

Design of a Novel&nbsp;<em>&mu;</em>-Mixer

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Product

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Design of a Novel <em>μ</em>-Mixer