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PrefaceThe Defense Centers of Excellence for Psychological Health and Traumatic Brain Injury is interested in determining the efficacy and comparative effectiveness of integrative medicine approaches for psychological health conditions. This document is a systematic review of the efficacy of meditation interventions for posttraumatic stress disorder. The review will be of interest to military health policymakers and practitioners, civilian health care providers, and policymakers, payers, and patients.None of the authors has any conflicts of interest to declare. This research was sponsored by the Defense Centers of Excellence for Psychological Health and Traumatic Brain Injury and conducted within the Forces and Resources Policy Center of the RAND National Defense Research Institute, a federally funded research and development center sponsored by the Office of the Secretary of Defense, the Joint Staff, the Unified Combatant Commands, the Navy, the Marine Corps, the defense agencies, and the defense Intelligence Community. For more information on the RAND Forces and Resources Policy Center, see http://www.rand.org/nsrd/ndri/centers/frp.html or contact the director (contact information is provided on the web page).v Abstract Posttraumatic stress disorder (PTSD) is a debilitating condition that emerges after exposure to a traumatic event. Meditation may provide a safe, self-administered, and inexpensive complement to first-line treatments for PTSD. This systematic review synthesized evidence on meditation interventions for the treatment of PTSD (PROSPERO 2015: CRD42015025782).We searched eight electronic databases from inception to November 2015 and bibliographies of existing systematic reviews to identify English-language randomized controlled trials (RCTs) evaluating the efficacy and safety of meditation interventions in patients with PTSD. Two independent reviewers screened identified literature using prede...