A spindle cell sarcoma of liver supplied by internal mammary artery

Chen, J.; Zhang, J.; Dowell, Joshua D.; Wei, Xi; Zhang, X.; Chen, S.

doi:10.1016/j.diii.2014.06.002

Cited by 3 publications

(4 citation statements)

References 6 publications

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“…Hierzu zählen unter anderem Synovialsarkome, der desmoplastische klein-und rundzellige Tumor und das alveoläre Weichteilsarkom [248,249,250,251,252,253]. Ebenfalls existieren Berichte über Spindelzelltumoren, die nicht näher differenziert werden konnten und somit aus dieser Auflistung ausgeschlossen wurden [13,14]. Die Beschreibung eines desmoplastischen klein-und rundzelligen Tumors der Leber betraf einen 16-jährigen Patienten und wurde aus dieser Auflistung ausgeschlossen [248].…”

Section: Tumoren Mit Unsicherer Differenzierung Und Anders Klassifizi...unclassified

“…Der minimale Abstand des Tumors zum Schnittrand hängt von verschiedenen Faktoren wie Entität, Grading, präoperativen Therapien und anatomischen Grenzen ab. Unter bestimmten Umständen kann eine marginale Resektion akzeptiert werden, jedoch gilt die generelle Empfehlung zur weiten Exzision [13,14,15]. Bezüglich des Sicherheitsabstands in der Leberchirurgie wie auch zur systematischen Lymphadenektomie im Bereich des Lig.…”

Section: Management Der Lokalen/lokoregionalen Erkrankungunclassified

“…Angiosarkome-[9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40, 4166,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,…”

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Primäre Lebersarkome – Empfehlungen zur chirurgischen Therapie

et al. 2022

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Section: Tumoren Mit Unsicherer Differenzierung Und Anders Klassifizi...unclassified

Section: Management Der Lokalen/lokoregionalen Erkrankungunclassified

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Primäre Lebersarkome – Empfehlungen zur chirurgischen Therapie

et al. 2022

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“…breast [8], major pulmonary arteries [9], maxilla [10], frontal sinus [11], parotid gland [12], prostate [13], thyroid [14], oesophagus [15], larynx [16], liver [17], and heart [18], have been described. Their rates of survival and prognostic factors are supposed to be different by site.…”

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confidence: 99%

A nomogram to predict the individual outcomes of spindle cell sarcoma originated in limbs

Sun

Hong

et al. 2022

Preprint

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Background Spindle cell sarcoma is a relatively rare type of sarcoma that mostly originates in soft tissues, but it tends to grow rapidly, and its clinical treatment is a major challenge. From previous reports in the literature, this type of sarcoma has a high proportion of cases affecting the limbs, and research on this topic has potential clinical value. The present study developed a nomogram to effectively predict the survival of patients and analyse the independent prognostic factors of primary limb spindle cell sarcoma.Methods The clinical information of 748 primary limb spindle cell sarcoma patients was obtained from the SEER database. After applying the inclusion/exclusion criteria, 542 patients were included in our study, and they were divided into a training group and a validation group at a ratio of 2:1. The X-tile program was used to determine the best cut-off point for age and tumour size. Univariate and multivariate analyses were used to determine independent prognostic factors, and the training group data were used to construct a nomogram to predict patients’ overall survival and cancer-specific survival. The training cohort data were used for internal verification of the nomogram, and the validation cohort data were used for external verification of the nomogram. The C index was used to calculate the predictive performance of the nomogram. Additionally, we built an online forecasting website.Results The primary limb spindle cell sarcoma has high proportion of all spindle cell sarcoma, and it may have potential associations with pathologic fractures, then marital status, age, historic stage, tumour size and surgical type were identified as five independent prognostic factors, and combined with these factors, a nomogram was constructed for predicting 5-year and 10-year overall survival rates and cancer-specific survival rates. The overall survival rate and tumour-specific survival rate prediction internal validation consistency index (C index) was 0.824 (95% CI 0.794-0.854) and 0.854 (95% CI 0.825-0.883), while the externally validated C index was 0.765 (95% CI 0.706-0.824) and 0.766 (95% CI 0.700-0.832), respectively. Additionally, in order to make the nomogram more convenient and accurate, an online website was created where after entering basic clinical information. The website can help clinicians provide guidance to patients who have these rare sarcomas.Conclusions The nomogram constructed for primary limb spindle cell sarcoma can predict the survival of these patients.

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Spindle cell sarcoma: a SEER population-based analysis

Feng

Wang

Yibulayin

et al. 2018

Sci Rep

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Due to the substantial limitation of study population, Spindle cell sarcoma (SCS) was unexplored comprehensively. In this study, we investigated the clinical characteristics and disease specific prognostic factors of SCS. 3299 SCS cases were identified and extracted from Surveillance, Epidemiology, and End Results (SEER) database (1973–2017). White people account for 79.1% with median age of 57 years without predominance in any gender. Significant disease specific survival (DSS) and overall survival (OS) were found differentiated in age, T stage, N stage, M stage, AJCC stage, SEER historic stage, tumor locations, surgery, and pathologic grade. In the multivariate Cox analysis, the age >64 years (for DSS, P < 0.001 and for OS, P < 0.001; Reference age ≤64 years), AJCC stage III (for DSS, P = 0.006 and for OS, P = 0.04; Reference: AJCC stage I), and non-surgical treatment (for DSS, P < 0.001 and for OS, P < 0.001; Reference: surgery) were independently associated with worse DSS and OS. In brief, our study demonstrated that SCS mostly found in white people at fifth to seventh decades of life without gender predilection. The patient’s age, AJCC stage, tumor location and surgery were independent prognostic indicators for both DSS and OS of SCS.

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A spindle cell sarcoma of liver supplied by internal mammary artery

Cited by 3 publications

References 6 publications

Primäre Lebersarkome – Empfehlungen zur chirurgischen Therapie

Primäre Lebersarkome – Empfehlungen zur chirurgischen Therapie

A nomogram to predict the individual outcomes of spindle cell sarcoma originated in limbs

Spindle cell sarcoma: a SEER population-based analysis

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