A Spectrophotometric Study of the Schiff Reaction as Applied to the Quantitative Determination of Sulfur Dioxide

Nauman, R. V.; West, Philip W.; Tron, Francois.; Gaeke, G. C.

doi:10.1021/ac60166a023

Cited by 102 publications

(37 citation statements)

References 7 publications

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“…The 'Hmr spectrum in DMSO-ti, of material prepared by this method, however. indicates that the correct structure is 14: The spectral evidence leaves no doubt that this complex is a 1 : 1 adduct of structure 14 in agreement with more recent formulations of the coloured Schiff product as an a-aminosulfonic acid (9,11). However, Wieland and Scheuing state that the actual dye is a 2: 1 (aldehyde-pararosaniline) adduct (7) and Hoi-mann et al have found that the colour developed is proportional to the square of the acetaldehyde concentration (9).…”

Section: Scl~iff Reagent Acetaldehyde Addition Productsupporting

confidence: 85%

The structure of Schiff reagent aldehyde adducts and the mechanism of the Schiff reaction as determined by nuclear magnetic resonance spectroscopy

Robins¹,

Abrams²,

Pincock³

1980

Can. J. Chem.

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An nmr study of compounds isolated from the Schiff aldehyde reaction between pararosaniline hydrochloride, sulfur dioxide, and acetaldehyde has demonstrated that these adducts are α-anilinoalkylsulfonic acids. The evidence is incompatible with the other structures most often accepted in the literature, N-phenyl alkylsulfonamides. In combination with nmr spectra obtained from solutions of the Schiff reagent and the Schiff reaction and with literature spectrophotometric data, this result leads to a reasonable proposal for the mechanism of the colour development. The effects of the concentrations of the dye, acetaldehyde, and in particular, sulfur dioxide are explained and suggest that the dominant coloured species is a 2:1 acetaldehyde–dye adduct. The nmr results also reveal a kinetic/thermodynamic competition for acetaldehyde between the aniline of the dye and the aldehyde carbonyl leading to bisulfite addition. The relation of the Schiff test with acetaldehyde and the Feulgen test for aldehydes in biological samples is also discussed.

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Section: Scl~iff Reagent Acetaldehyde Addition Productsupporting

confidence: 85%

The structure of Schiff reagent aldehyde adducts and the mechanism of the Schiff reaction as determined by nuclear magnetic resonance spectroscopy

Robins¹,

Abrams²,

Pincock³

1980

Can. J. Chem.

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“…Pararosaniline was immediately reduced to a colourless solution when combined with dilute HCl. Previous studies [26][27][28] have examined the reaction mechanism of Schiff's reaction and in line with these theories it is proposed that protonation of pararosaniline (A) resulted in the cationic species represented by the canonical forms for the resonance structure (D) (see Fig. 1).…”

Section: Preparation and Examination Of Schiff's Reagent Chemistrymentioning

confidence: 83%

“…All results reported here were blank corrected by subtracting the A aq value of blank solutions from the A aq value of exposed solutions. Exposed aliquots of reagent were removed from the environment after set periods of time (13,26,78,158 or 285 min) and the A aq values for each solution measured using the bench top spectrometer. The regression coefficients obtained are given in Table 1.…”

Section: Colourimetric Reagent Response To Vapour Phase Formaldehydementioning

confidence: 99%

On-site determination of formaldehyde: A low cost measurement device for museum environments

Gibson

Kerr

Nordon

et al. 2008

Analytica Chimica Acta

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“…In exposure chamber studies, use has been made of a metered gas delivery system [27], analytical chemical methods [11,[28][29][30], gas adsorbent tubes [31,32] and gas analysers [33][34][35], or other gas sensors providing a continuous read-out. Our choice of gas sensor was influenced by three factors, namely reliability, sensitivity and cost.…”

Section: Discussionmentioning

confidence: 99%

A method for the long-term exposure of rabbits to environmental pollutant gases

Douglas

Price²,

Page³

1994

Eur Respir J

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A A m me et th ho od d f fo or r t th he e l lo on ng g--t te er rm m e ex xp po os su ur re e o of f r ra ab bb bi it ts s t to o e en nv vi ir ro on nm me en nt ta al l p po ol ll lu ut ta an nt t g ga as se es s ABSTRACT: The aims of the present study were twofold. Firstly, we wanted to develop a system for the exposure of rabbits to pollutant gases that would monitor gas concentrations accurately, allow flexibility, be simple to operate, and could be constructed at relatively modest cost. Additionally, we wanted to determine whether the procedures necessary for the daily exposure of young rabbits had any detrimental effect on their development. Using the environmental exposure system that we developed, littermate New Zealand White rabbits, neonatally immunized to either Alternaria tenuis or house dust mite antigen were exposed 2 h daily, from within 24 h of birth until 3 months of age, to either 4 ppm nitrogen dioxide (NO 2 ), or 5 ppm sulphur dioxide (SO 2 ) or ambient air.The environmental exposure system consists of four sections; a stainless steel exposure chamber; an airflow monitoring and control system and gas delivery system; a gas detector and monitoring system; and an exhaust fan. Equilibration and wash-out times of gas were short and the gas mixing within the chamber atmosphere was uniform. Levels of gases were reliably maintained throughout the period of exposure within predetermined limits. The weights of the immunized, gas-exposed animals did not differ significantly from those of the immunized, airexposed animals at any time throughout the 3 month period of exposure. At 3 months of age, the basal values for lung resistance and dynamic compliance did not differ between gas-and air-exposed rabbits. These values did not differ significantly from those obtained from naive animals of the same age.Our results suggest that we have developed a sensitive, reliable and simple environmental exposure and monitoring system. It is anticipated that the methodology described will allow the careful investigation of the effects of long-term exposure to pollutant gases from birth on the development of airways hyperresponsiveness.

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A Spectrophotometric Study of the Schiff Reaction as Applied to the Quantitative Determination of Sulfur Dioxide

Cited by 102 publications

References 7 publications

The structure of Schiff reagent aldehyde adducts and the mechanism of the Schiff reaction as determined by nuclear magnetic resonance spectroscopy

The structure of Schiff reagent aldehyde adducts and the mechanism of the Schiff reaction as determined by nuclear magnetic resonance spectroscopy

On-site determination of formaldehyde: A low cost measurement device for museum environments

A method for the long-term exposure of rabbits to environmental pollutant gases

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