“…Sir: Several methods for the standardization of histamine solutions have been reported in recent literature (3)(4)(5). Most of these are colorimetric techniques which are time consuming, both with respect to procedure and reagent preparation.…”
Section: Polarographic Standardization Of Aqueous Histamine Solutionsmentioning
“…Sir: Several methods for the standardization of histamine solutions have been reported in recent literature (3)(4)(5). Most of these are colorimetric techniques which are time consuming, both with respect to procedure and reagent preparation.…”
Section: Polarographic Standardization Of Aqueous Histamine Solutionsmentioning
“…A colorimetric assay for histamine based on its reaction with diazotized pbromoaniline is reported (390). In a similar procedure (SO) preliminary extractions of protein-free samples with ether and amyl alcohol permit the determination of histamine in blood samples.…”
“…These methods depend chiefly upon the light absorbance of the coupling product of histamine and a diazonium ion in alkaline media or the reaction product of hista-mine with dinitrofluorobenzene (5, 7). Substituted phenyldiazonium ions that have been used successfully include p-sulfonic acid (2, S), p-bromo- (1,6), and p-nitro- (10,11). Certain metallic ions, principally cobalt(II), copper(I), copper(II), nickel(II), and iron(III), cause interference in each of the above methods by forming a stable complex with histamine (8, 9).…”
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