1990
DOI: 10.1159/000195869
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A Solitary Pulmonary Nodule due to <i>Mycobacterium gordonae</i>

Abstract: Mycobacterium gordonae is rarely pathogenic in humans. In this case it was cultured from the tissue of a resected pulmonary nodule in an immunocompetent patient. One year after completing 12 months of chemotherapy, the patient remains disease free. Atypical mycobacterium should be considered in the differential diagnosis of solitary pulmonary nodules.

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Cited by 12 publications
(7 citation statements)
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References 12 publications
(15 reference statements)
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“…After 2 weeks, sarcoid-like granulomas had formed from epitheloid and giant cells without casefying necroses. These findings are comparable to the histology of those cases with documented lung biopsy [11,16,20,24], Further more, such lesions are in agreement with nodules shown by UF-CT in the present case.…”
Section: Discussionsupporting
confidence: 92%
“…After 2 weeks, sarcoid-like granulomas had formed from epitheloid and giant cells without casefying necroses. These findings are comparable to the histology of those cases with documented lung biopsy [11,16,20,24], Further more, such lesions are in agreement with nodules shown by UF-CT in the present case.…”
Section: Discussionsupporting
confidence: 92%
“…14 Prior reports of pulmonary infection caused by M gordonae have generally been limited in scope and have incompletely defined the patient population at risk. [3][4][5][6][7][8][9][10][11][12][13] Some reports have, however, presented clinical and microbiological data that meet proposed, although poorly validated, case definitions of nontuberculous mycobacterial pulmonary infection causing disease. 14,15 For example, Kumar Radiographic findings were attributed to old pulmonary MTB and asbestos exposure.…”
Section: Discussionmentioning
confidence: 99%
“…While M gordonae is generally viewed as having low pathogenic potential, there have been a number of limited reports of infection causing pulmonary disease in humans. [3][4][5][6][7][8][9][10][11][12][13] Host risk factors for either respiratory tract colonization or pulmonary disease have not, however, been defined. Abnormal lung architecture and host immunity may be important factors.…”
mentioning
confidence: 99%
“…Of two patients with lung lesions attributed to M. gordonae, one yielded multiple isolates of the organism from sputum (31), but the strain was not described in detail; in the other patient, the strain was isolated from a resected nodule (35) and was urease positive, which is very unusual for M. gordonae. Four isolations from pleural effusions have been reported (71): two associated with malignant disease, one associated with congestive heart failure, and the other of unknown origin but which resolved without treatment.…”
Section: Species Of Mycobacteria Generallymentioning
confidence: 97%