A soft-magnet-based drug-delivery module for active locomotive intestinal capsule endoscopy using an electromagnetic actuation system

Le, Viet Ha; Leon-Rodriguez, Hernando; Lee, Cheong; Go, Gwangjun; Jin, Zhen; Nguyen, Van Du; Choi, Hyun‐Chul; Ko, Seong Young; Park, Jong-Oh; Park, Sukho

doi:10.1016/j.sna.2016.03.020

Cited by 54 publications

(14 citation statements)

References 18 publications

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“…The present drug delivery vehicle has good drug-loading capability and can conquer unfavorable distribution throughout the body, which is common for other drug delivery vehicles of much larger size. 8 Sometimes, the modification of NP properties is used to decrease harmful effects. For example, biodegradable iron stents have great potential to reduce limitations, such as chronic inflammation and premature recoil.…”

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confidence: 99%

A review of drug delivery systems based on nanotechnology and green chemistry: green nanomedicine

Jahangirian

Lemraski

Webster

et al. 2017

IJN

440

216

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This review discusses the impact of green and environmentally safe chemistry on the field of nanotechnology-driven drug delivery in a new field termed “green nanomedicine”. Studies have shown that among many examples of green nanotechnology-driven drug delivery systems, those receiving the greatest amount of attention include nanometal particles, polymers, and biological materials. Furthermore, green nanodrug delivery systems based on environmentally safe chemical reactions or using natural biomaterials (such as plant extracts and microorganisms) are now producing innovative materials revolutionizing the field. In this review, the use of green chemistry design, synthesis, and application principles and eco-friendly synthesis techniques with low side effects are discussed. The review ends with a description of key future efforts that must ensue for this field to continue to grow.

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mentioning

confidence: 99%

A review of drug delivery systems based on nanotechnology and green chemistry: green nanomedicine

Jahangirian

Lemraski

Webster

et al. 2017

IJN

440

216

View full text Add to dashboard Cite

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“…A module for drug delivery that is combined with the ALICE [25] system has been presented by the group of Le et al [38]. The drug delivery module consists of two ring-type soft magnets and a simple plastic hinge.…”

Section: Soft-magnet-based Drug-delivery Module For the Alice Systemmentioning

confidence: 99%

The future of capsule endoscopy in clinical practice: from diagnostic to therapeutic experimental prototype capsules

Vasilakakis

Koulaouzidis

Marlicz

et al. 2020

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Capsule endoscopy (CE) is indicated as a first-line clinical examination for the detection of small-bowel pathology, and there is an ever-growing drive for it to become a method for the screening of the entire gastrointestinal tract (GI). Although CE's main function is diagnosis, the research for therapeutic capabilities has intensified to make therapeutic capsule endoscopy (TCE) a target within reach. This manuscript presents the research evolution of CE and TCE through the last 5 years and describes notable problems, as well as clinical and technological challenges to overcome. This review also reports the state-of-the-art of capsule devices with a focus on CE research prototypes promising an enhanced diagnostic yield (DY) and treatment. Lastly, this article provides an overview of the research progress made in software for enhancing DY by increasing the accuracy of abnormality detection and lesion localisation. The future of capsule endoscopy-experimental devices for diagnosis and therapy Gastroenterology Review

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“…However, our simulation results using the iron alloy (such as Fe@Au alloy) also indicated the doping effects similar to that of the pure iron (please refer to the Effect of the releasing composition section). Some drug delivery researchers also used pure iron in their studies because of its high magnetic stability and high permeability . We also intend to apply the magnetic field to investigate the drug delivery process with the magnetic nanoparticles (iron nanoclusters) in the future work and compare the results with this research.…”

Section: Simulation Detailsmentioning

confidence: 99%

Molecular dynamics simulation of anticancer drug delivery from carbon nanotube using metal nanowires

et al. 2019

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In this study, we have investigated delivery of cisplatin as the anticancer drug molecules in different carbon nanotubes (CNTs) in the gas phase using molecular dynamics simulation. We examined the shape and composition of the releasing agent by using the different nanowires and nanoclusters. We also investigated the doping effect on the drug delivery process using N-, Si, B-, and Fe-doped CNTs. Different thermodynamics, structural, and dynamical properties have been studied by using the pure and different doped CNTs in this study. Our results show that the doping of the CNT has significant effect on the rate of the drug releasing process regardless of the composition of the releasing agent.

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A soft-magnet-based drug-delivery module for active locomotive intestinal capsule endoscopy using an electromagnetic actuation system

Cited by 54 publications

References 18 publications

A review of drug delivery systems based on nanotechnology and green chemistry: green nanomedicine

A review of drug delivery systems based on nanotechnology and green chemistry: green nanomedicine

The future of capsule endoscopy in clinical practice: from diagnostic to therapeutic experimental prototype capsules

Molecular dynamics simulation of anticancer drug delivery from carbon nanotube using metal nanowires

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