A social cognitive theory-based framework for monitoring medication adherence applied to endocrine therapy in breast cancer survivors

Abstract

Poor adherence to long-term therapies for chronic diseases, such as cancer, compromises effectiveness of treatment and increases the likelihood of disease progression, making medication adherence a critical issue in population health. While the field has documented many eers to adherence to medication, it has also come up with few efficacious solutions to medication adherence, indicating that new and innovative approaches are needed. In this paper, we evaluate medication-taking behaviors based on social cognitive theory (SCT), presenting patterns of adherence stratified across SCT constructs in 33 breast cancer survivors over an 8-month period. Findings indicate that medication adherence is a very personal experience influenced by many simultaneously interacting factors, and a deeper contextual understanding is needed to understand and develop interventions targeting non-adherence.

Health Information Technology Supporting Adherence Memory Disorder Patients: A Systematic Literature Review

“…Information regarding the population was reported as age and disease. 28 29 To report the findings related to the role of technology in supporting medication adherence among the population selected, we used two frameworks adopted for this use case. We used the framework of Eicher et al 30 developed to classify the strategies adopted to improve medication adherence through technology applications.…”

An Adaptable Framework for Factors Contributing to Medication Adherence: Results from a Systematic Review of 102 Conceptual Frameworks

“… 16 – 19 The five dimensions are patient-related factors, medication-related factors, condition-related factors, healthcare system/healthcare provider (HCP)-related factors, and socioeconomic factors. We identified prominent patient groups in our included studies based on age (adult/pediatrics) and type of disease condition as medication adherence varies by age, 9 and the type of disease condition may influence perceived disease threat and health risk, 20 which in turn impacts adherence behavior. 21 The review team discussed and synthesized information in an iterative process, considering the strengths and weaknesses of each conceptual model, as well as common factors and gaps across models in each patient group.…”

“… 8 Adherence to medications also varies by age; younger patients appear to have better adherence than older patients. 9 In children, adherence to drug therapy is also affected by their dependence on an adult caregiver. 8 …”

Leveraging Mobile Sensing to Understand and Develop Intervention Strategies to Improve Medication Adherence

“…In addition, individuals who are poorly informed about side effects are less likely to adhere to any medication, including endocrine therapy, and that updating patients' knowledge regularly can improve adherence. [3]. Affective states associated with lack of adherence to medications are distress, depression, and fear of cancer recurrence [11], [18].…”

“…Preliminary work from our team has already yielded rich insights into medication-taking behavior patterns and represents a key first step toward building the MMI framework on SCT constructs. Boukhechba et al analyzed data assessing medication adherence of 33 breast cancer survivors taking endocrine therapy medication using MEMS over an eight-month period [3]. These results indicate that breast cancer survivors have diverse patterns of medication-taking behavior over the course of the monitoring period.…”