A Snapshot of the Most Recent Transthyretin Stabilizers
Carlo Marotta,
Lidia Ciccone,
Elisabetta Orlandini
et al.
Abstract:In recent years, several strategies have been developed for the treatment of transthyretin-related amyloidosis, whose complex clinical manifestations involve cardiomyopathy and polyneuropathy. In view of this, transthyretin stabilizers represent a major cornerstone in treatment thanks to the introduction of tafamidis into therapy and the entry of acoramidis into clinical trials. However, the clinical treatment of transthyretin-related amyloidosis still presents several challenges, urging the development of new… Show more
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