“…The proposed device is an upgraded version of a previously in-house developed intrinsic fluorescence detection probe using spectrometer as a detector 17 , 36 , 37 . The device can be divided into two chambers: input chamber and output chamber as shown by the schematic and working set-up of the device in Fig.…”
Section: Methodsmentioning
confidence: 99%
“…Spectra of all these lasers and that of a continuous Xenon lamp light source, collected both from the smartphone and a commercial spectrometer (USB 4000, Ocean Optics), are shown for comparison in Fig. 2 a,b 37 . Figure 2 Spectra of four different lasers and Xe-lamp from ( a ) smartphone and ( b ) spectrometer.…”
Fluorescence spectroscopy has the potential to identify discriminatory signatures, crucial for early diagnosis of cervical cancer. We demonstrate here the design, fabrication and testing of a 3D printed smartphone based spectroscopic device. Polarized fluorescence and elastic scattering spectra are captured through the device using a 405 nm laser and a white LED source respectively. The device has been calibrated by comparison of spectra of standard fluorophores (Flavin adenine dinucleotide, fluorescein, rhodamine, and porphyrin) with the corresponding spectra collected from a commercial spectrometer. A few cervical tissue spectra have also been captured for proof of its applicability as a portable, standalone device for the collection of intrinsic fluorescence spectra from human cervix.
“…The proposed device is an upgraded version of a previously in-house developed intrinsic fluorescence detection probe using spectrometer as a detector 17 , 36 , 37 . The device can be divided into two chambers: input chamber and output chamber as shown by the schematic and working set-up of the device in Fig.…”
Section: Methodsmentioning
confidence: 99%
“…Spectra of all these lasers and that of a continuous Xenon lamp light source, collected both from the smartphone and a commercial spectrometer (USB 4000, Ocean Optics), are shown for comparison in Fig. 2 a,b 37 . Figure 2 Spectra of four different lasers and Xe-lamp from ( a ) smartphone and ( b ) spectrometer.…”
Fluorescence spectroscopy has the potential to identify discriminatory signatures, crucial for early diagnosis of cervical cancer. We demonstrate here the design, fabrication and testing of a 3D printed smartphone based spectroscopic device. Polarized fluorescence and elastic scattering spectra are captured through the device using a 405 nm laser and a white LED source respectively. The device has been calibrated by comparison of spectra of standard fluorophores (Flavin adenine dinucleotide, fluorescein, rhodamine, and porphyrin) with the corresponding spectra collected from a commercial spectrometer. A few cervical tissue spectra have also been captured for proof of its applicability as a portable, standalone device for the collection of intrinsic fluorescence spectra from human cervix.
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