A compact coupled-fed handset antenna with multi-frequency band operation is proposed in this paper. It occupies a no-ground space of only 26 × 14 mm 2 , and two wideband operations can be achieved by the coupled-fed two opposite-direction spiral branches. The low frequency bands of LTE700 operation are achieved by two spiral branches' 0.25-wavelength monopole modes, which generate a dual-resonance mode at 740 and 780 MHz. At around high frequency ranges, a 0.25wavelength monopole mode of a T-shaped monopole is generated at 1.75 GHz, and combined with two 0.75-wavelength high-order monopole modes of the left and right side spiral branches to cover the DCS1800/PCS1900/UMTS2100/LTE2300/2500 bands. In addition, the proposed antenna is easily printed on the dielectric surface of a low cost FR4 substrate, which makes it suitable for practical mobile applications. The proposed antenna is successfully simulated, fabricated, and measured to validate the design.