A six-year sleep lab experience in an Egyptian University Hospital

Yousif, Maha; El-Helbawy, Rana

doi:10.1016/j.ejcdt.2013.09.006

Cited by 4 publications

(5 citation statements)

References 12 publications

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“…A recent study that included around 1000 patients referred for polysomnography in Cairo, Egypt, found that 83% of the patients were diagnosed with OSA, agreeing with similar results elsewhere in Egypt [11][12][13][14]. Even though these studies were retrospective, single centered, and their results cannot be projected on the entire population but at least confirming that OSA is the most common sleep disorder encountered in hospitals and clinics around Egypt and special attention must be given to it.…”

Section: Introductionsupporting

confidence: 63%

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The deleterious effects of chronic obstructive pulmonary disease and obstructive sleep apnea: pathophysiology and implications on treatment

Gharib

2020

Egypt J Bronchol

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Background: Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) are both common in the adult population. The coexistence and association of both COPD and OSA have been described as the overlap syndrome. The scope of the present review is to address the magnitude, pathophysiology, clinical presentations, and the deleterious consequences of the coexistence of COPD and OSA in the same patient as well as the current management and treatment options of this association. Main body of abstract: Epidemiological studies showed a prevalence of the overlap syndrome of up to 1% of the adult population. However, various studies agreed that this association is due to the fact that both COPD and OSA are common rather than an interaction of pathophysiology between the two affections. Nevertheless, sleep may cause adverse effects on breathing and lung functions. While these effects can be neglected in otherwise healthy individuals, they can lead in contrast to disastrous clinical outcomes particularly in vulnerable patients with the overlap syndrome leading to increased risk of cardiovascular diseases, acute COPD exacerbations, increased rates of hospitalizations, and nocturnal deaths. Current guidelines recommend polysomnography (PSG) as the gold standard investigation to diagnose sleep disorders and overlap syndrome. Treatment may include pulmonary rehabilitation, supplemental oxygen therapy, and non-invasive ventilation. Currently, continuous positive airway pressure (CPAP) therapy is the treatment of choice for the overlap syndrome. CPAP effects include improved respiratory mechanics; sleep quality, exercise tolerance, and prolonged survival. Conclusion: Both COPD and OSA are common in the general population and present a significant risk of increased morbidity and mortality when they coexist in the same patient. Clinicians must carefully evaluate the clinical outcomes and the high risk of cardiovascular complications related to the overlap syndrome. Current data indicate that CPAP treatment leads to amelioration of the health-related quality of life and improve survival in patients with the overlap syndrome.

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Section: Introductionsupporting

confidence: 63%

“…Regarding the OS in Egypt, to the present author's knowledge, only three studies while assessing comorbidities associated with OSA noted different incidence figures of COPD among their patients varying between 4, 16, and 57% [13,24,25].…”

Section: Epidemiologymentioning

confidence: 63%

The deleterious effects of chronic obstructive pulmonary disease and obstructive sleep apnea: pathophysiology and implications on treatment

Gharib

2020

Egypt J Bronchol

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“…Comparison between the two sexes revealed that females were older than males (58.87 ± 10. 25 72, p = 0.001), and severe OSA was commonly diagnosed in men than in women (p = 0.001) as seen in Fig. 1.…”

Section: Differences Between Males and Femalesmentioning

confidence: 80%

“…In the delta region, a study which included 50 patients found that 80% of them had OSA [24]. Also, in another work in the same region, an equal figure was found in a sample of 400 patients [25]. Authors from Alexandria evaluated 32 patients with tachyarrythmias by a level III sleep study and diagnosed 84% with OSA [26].…”

Section: Discussionmentioning

confidence: 98%

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Factors affecting the severity of the apnea hypoapnea index: a retrospective study on 838 Egyptian patients diagnosed with obstructive sleep apnea

Gharib

Loza

2020

Egypt J Bronchol

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Background Obstructive sleep apnea (OSA) is a common condition in the general population that is highly correlated to obesity, and it is associated with major cardiovascular morbidity and mortality. In Egypt, obesity rates are known to be high; however, OSA remains largely under-diagnosed, and data on its current magnitude is very scarce. Thus, the aims of the study were to identify the percentage of OSA in a large sample of patients referred for polysomnography and to determine the effect of different demographic data on the severity of the disease. Results This retrospective study included 1012 patients. Medical data were reviewed by sleep specialists. The correlation between age, body mass index (BMI), and neck circumference (NC) with apnea hypoapnea index (AHI) was explored. Also, gender differences were analyzed. A total of 838 patients (81% males, 19% females) were diagnosed with OSA. Patients with mild, moderate, and severe OSA were 204 (24%), 146 (17%), and 488 (58%), respectively. Females were older than males (58.87 ± 10.25 versus 54.39 ± 22.96, p = 0.001) and BMI was not significantly different between both sexes (34.18 ± 13.53 versus 36.73 ± 23.25, p = 0.07), but NC was higher in men (43.56 ± 5.3 versus 39.34 ± 4.41, p = 0.001). AHI was significantly increased in men compared to women (47.97 ± 31.22 versus 37.95 ± 31.72, p = 0.001) and severe OSA was commonly diagnosed in men than women (p = 0.001). A positive significant correlation was found between BMI, NC with AHI, arousal index, average SpO2, and desaturation index. Conclusion OSA is highly prevalent among our patients. Additionally, BMI and NC independently affected the severity of their disease.

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Comorbidities associated with obstructive sleep apnea: a retrospective Egyptian study on 244 patients

et al. 2019

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A six-year sleep lab experience in an Egyptian University Hospital

Cited by 4 publications

References 12 publications

The deleterious effects of chronic obstructive pulmonary disease and obstructive sleep apnea: pathophysiology and implications on treatment

The deleterious effects of chronic obstructive pulmonary disease and obstructive sleep apnea: pathophysiology and implications on treatment

Factors affecting the severity of the apnea hypoapnea index: a retrospective study on 838 Egyptian patients diagnosed with obstructive sleep apnea

Comorbidities associated with obstructive sleep apnea: a retrospective Egyptian study on 244 patients

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