A Single Preoperative Dose of Gabapentin (800 Milligrams) Does Not Augment Postoperative Analgesia in Patients Given Interscalene Brachial Plexus Blocks for Arthroscopic Shoulder Surgery

Adam, Frédéric; Ménigaux, C.; Sessler, Daniel I.; Chauvin, M.

doi:10.1213/01.ane.0000237300.78508.f1

Cited by 72 publications

(63 citation statements)

References 25 publications

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“…Turan et al (23) found that GBP (1200 mg/day) as an adjunct to epidural analgesia decreased pain and analgesic consumption in patients who had undergone lower extremity surgical procedures. In contrast, Adam et al (17) found that a single preoperative dose of 800 mg of GBP did not augment postoperative analgesia in patients given interscalene brachial plexus blocks for arthroscopic shoulder surgery. It is clear that administration of GBP in conjunction with regional anesthesia needs further investigation with respect to the timing and length of postoperative administration.…”

Section: Discussionmentioning

confidence: 90%

“…Over the past eight years, many trials have examined the efficacy of GBP for the treatment of early postsurgical pain. The surgical populations studied include abdominal or pelvic surgery (9-16), musculoskeletal surgery (5,(17)(18)(19)(20)(21)(22)(23), head and neck surgery (24)(25)(26), breast surgery (27)(28)(29)(30), varicocele surgery (31) and thoracic surgery (32). Of these randomized controlled trials, most consisted of a single dose of GBP given before surgery.…”

mentioning

confidence: 99%

“…Of these randomized controlled trials, most consisted of a single dose of GBP given before surgery. Only four of the above trials failed to demonstrate a decrease in pain scores or an opioidsparing effect in the early postsurgical period (10,17,18,21).…”

mentioning

confidence: 99%

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Gabapentin decreases morphine consumption and improves functional recovery following total knee arthroplasty

Clarke¹,

Pereira²,

Kennedy³

et al. 2009

Acute Pain

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Section: Discussionmentioning

confidence: 90%

mentioning

confidence: 99%

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Gabapentin decreases morphine consumption and improves functional recovery following total knee arthroplasty

Clarke¹,

Pereira²,

Kennedy³

et al. 2009

Acute Pain

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“…The surgical populations studied include abdominal or pelvic surgery, 111-118 musculoskeletal surgery, [119][120][121][122][123][124][125][126] 135 and, recently, cardiac surgery. 136 Of these randomized controlled trials, most consisted of a single dose of gabapentin given prior to surgery.…”

Section: Anticonvulsantsmentioning

confidence: 99%

“…Only four of the above trials failed to demonstrate a decrease in pain scores or an opioid-sparing effect in the early post-surgical period. 112,119,120,124 Recently, Mathiesen et al demonstrated the effectiveness of pregabalin in reducing opioid consumption after THA. 137 Several meta-analyses have confirmed that these anticonvulsants reduce both postoperative opioid use and postoperative pain scores.…”

Section: Anticonvulsantsmentioning

confidence: 99%

Strategies Aimed at Preventing Chronic Post-surgical Pain: Comprehensive Perioperative Pain Management after Total Joint Replacement Surgery

Clarke¹,

Woodhouse

Kennedy

et al. 2011

Physiotherapy Canada

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Purpose: Chronic post-surgical pain (CPSP) is a frequent outcome of musculoskeletal surgery. Physiotherapists often treat patients with pain before and after musculoskeletal surgery. The purposes of this paper are (1) to raise awareness of the nature, mechanisms, and significance of CPSP; and (2) to highlight the necessity for an inter-professional team to understand and address its complexity. Using total joint replacement surgeries as a model, we provide a review of pain mechanisms and pain management strategies. Summary of Key Points: By understanding the mechanisms by which pain alters the body's normal physiological responses to surgery, clinicians selectively target pain in post-surgical patients through the use of multi-modal management strategies. Clinicians should not assume that patients receiving multiple medications have a problem with pain. Rather, the modern-day approach is to manage pain using preventive strategies, with the aims of reducing the intensity of acute postoperative pain and minimizing the development of CPSP. Conclusions: The roles of biological, surgical, psychosocial, and patient-related risk factors in the transition to pain chronicity require further investigation if we are to better understand their relationships with pain. Measuring pain intensity and analgesic use is not sufficient. Proper evaluation and management of risk factors for CPSP require inter-professional teams to characterize a patient's experience of postoperative pain and to examine pain arising during functional activities.Key Words: chronic post-surgical pain, inter-professional teams, multi-modal analgesia, preventive analgesia, total joint replacement RÉ SUMÉObjectif : La douleur chronique postopé ratoire est une consé quence fré quente de la chirurgie musculosquelettique. Les physiothé rapeutes traitent souvent les patients qui ressentent de la douleur avant et aprè s ce type d'intervention. L'objectif de cet article est (1) de sensibiliser à la nature, aux mé canismes et à l'importance de ce type de douleur chronique et (2) de souligner la né cessité , pour une é quipe interprofessionnelle, de comprendre et d'en maîtriser la complexité . Avec comme modè le les chirurgies de remplacement d'une articulation, nous avons analysé les mé canismes de la douleur et les straté gies pour sa gestion. Ré sumé des principaux points : En comprenant les mé canismes par lesquels la douleur affecte les ré ponses physiologiques normales à une intervention chirurgicale, les cliniciens ont ciblé de maniè re sé lective les patients souffrant de douleur postopé ratoire à l'aide de straté gies de gestion multimodales. Les cliniciens ne devraient pas dé duire que les patients qui reç oivent de multiples mé dicaments ont un problè me avec la douleur. L'approche moderne consiste plutô t à gé rer la douleur à l'aide de straté gies pré ventives qui visent à ré duire l'intensité de la douleur postopé ratoire aiguë et à minimiser les risques de dé veloppement de douleur chronique postopé ratoire. 289The authors have no conflicts...

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Antiépileptiques et antihyperalgésie péri-opératoire: état des lieux

Wattier

2013

La Douleur Chronique Post-Chirurgicale

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A Single Preoperative Dose of Gabapentin (800 Milligrams) Does Not Augment Postoperative Analgesia in Patients Given Interscalene Brachial Plexus Blocks for Arthroscopic Shoulder Surgery

Abstract: A single preoperative dose of gabapentin (800 mg) does not augment postoperative analgesia in patients given interscalene brachial plexus blocks for arthroscopic shoulder surgery.

Cited by 72 publications

References 25 publications

Gabapentin decreases morphine consumption and improves functional recovery following total knee arthroplasty

Gabapentin decreases morphine consumption and improves functional recovery following total knee arthroplasty

Strategies Aimed at Preventing Chronic Post-surgical Pain: Comprehensive Perioperative Pain Management after Total Joint Replacement Surgery

Antiépileptiques et antihyperalgésie péri-opératoire: état des lieux

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