A Single-Dose, Three-Period, Six-Sequence Crossover Study Comparing the Bioavailability Study of Dextromethorphan Hydrobromide Sustained Release (SR) Tablet and the Immediate Release (IR) Tablet in Healthy Volunteers Under Fasting Condition
Abstract:Objective was to compare pharmacokinetic characteristics of Sustained-Release (SR) and Immediate-Release (IR) formulations of dextromethorphan hydrobromide following a single oral administration of test and reference formulations in fasting healthy male volunteers. A randomized, 3-way, crossover, bioequivalence study was conducted in 6 healthy male volunteers to compare dextromethorphan hydrobromide Sustained Release (SR) tablet as test and the Immediate Release (IR) as reference product. Blood samples were co… Show more
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