A virtual laboratory application setup is used to control and monitor remotely the operation of several sensor nodes placed at different geographical locations. In this paper, we present the design of a generalized, low-cost and reconfigurable smart sensor node using a Zigbee with a Field-Programmable Gate Array (FPGA) that embeds all processing and communication functionalities based on the IEEE 1451 family of standards with communication taking place through a 1-wire protocol. The architecture of the sensor node is based on the single chip concept that includes communication, processing and transducer control functionalities. The proposed architecture reduces the physical size, power and increases speedup of processing due to inter-module communication. Results indicate the accuracy of the proposed system is tested with a temperature sensor which has 1-wire protocol.