2015
DOI: 10.1177/000313481508100336
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A Single-center Experience and Review of the Literature: 64 Cases of Phyllodes Tumors to Better Understand Risk Factors and Disease Management

Abstract: Phyllodes tumors of the breast are rare fibroepithelial tumors that are characterized as benign, borderline, or malignant based on cellular characteristics such as stromal overgrowth and number of mitoses. Currently, there is a lack of consensus on risk factors and management of patients with phyllodes tumors, which has led to variation in treatment patterns as well as patient outcomes across many institutions. This study seeks to understand the clinicopathologic features, risk factors for local and metastatic… Show more

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Cited by 10 publications
(13 citation statements)
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“…PT is a rare fibroepithelial tumor accounting for less than 1 % of all breast neoplasms [ 1 , 2 ]. They usually arise in women between ages 35 and 55 years and are classified as benign, borderline and malignant [ 2 , 3 ]. Malignant types present approximately 20 % of all cases [ 4 ].…”
Section: Discussionmentioning
confidence: 99%
See 3 more Smart Citations
“…PT is a rare fibroepithelial tumor accounting for less than 1 % of all breast neoplasms [ 1 , 2 ]. They usually arise in women between ages 35 and 55 years and are classified as benign, borderline and malignant [ 2 , 3 ]. Malignant types present approximately 20 % of all cases [ 4 ].…”
Section: Discussionmentioning
confidence: 99%
“…Metastatic PTs mainly develop from 3 to 10 years after the inital therapy, but they can be delayed or occur as soon as synchronous presentation [ 11 ]. The lung is the most common site of metastatic spread [ 2 , 3 , 15 ]. Only a few cases of PT metastatic to bone have been reported [ 6 ] with 2 cases involving the iliac bone [ 6 , 7 ] and 1 case involving the femur [ 8 ].…”
Section: Discussionmentioning
confidence: 99%
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“…Phyllodes tumors most often arise in patients in the 5 th decade of life and vastly more commonly in females [ 1 ]. They clinically present as a rapidly growing mass based in the breast, which is an important clue for diagnosis even if pathological diagnosis is inconclusive [ 2 ].…”
Section: Discussionmentioning
confidence: 99%