A simple webcam-based approach for the measurement of rodent locomotion and other behavioural parameters

Tort, Adriano Bretanha Lopes; Neto, Waldemar Pires Ferreira; Amaral, Olavo B.; Kazlauckas, Vanessa; Souza, Diogo O.; Lara, Diogo R.

doi:10.1016/j.jneumeth.2006.04.005

Cited by 36 publications

(26 citation statements)

References 28 publications

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“…The sessions were recorded with a webcam and locomotion during the task was calculated automatically using the MouseTracker software (Tort et al 2006). …”

Section: Open Field Explorationmentioning

confidence: 99%

Calcineurin inhibition blocks within-, but not between-session fear extinction in mice

et al. 2015

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Memory extinction involves the formation of a new associative memory that inhibits a previously conditioned association. Nonetheless, it could also depend on weakening of the original memory trace if extinction is assumed to have multiple components. The phosphatase calcineurin (CaN) has been described as being involved in extinction but not in the initial consolidation of fear learning. With this in mind, we set to study whether CaN could have different roles in distinct components of extinction. Systemic treatment with the CaN inhibitors cyclosporin A (CsA) or FK-506, as well as i.c.v. administration of CsA, blocked within-session, but not between-session extinction or initial learning of contextual fear conditioning. Similar effects were found in multiple-session extinction of contextual fear conditioning and in auditory fear conditioning, indicating that CaN is involved in different types of short-term extinction. Meanwhile, inhibition of protein synthesis by cycloheximide (CHX) treatment did not affect within-session extinction, but disrupted fear acquisition and slightly impaired between-session extinction. Our results point to a dissociation of within-and between-session extinction of fear conditioning, with the former being more dependent on CaN activity and the latter on protein synthesis. Moreover, the modulation of within-session extinction did not affect between-session extinction, suggesting that these components are at least partially independent.

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“…The sessions were recorded with a webcam and locomotion during the task was calculated automatically using the MouseTracker software (Tort et al 2006). …”

Section: Open Field Explorationmentioning

confidence: 99%

Calcineurin inhibition blocks within-, but not between-session fear extinction in mice

et al. 2015

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“…Among a variety of behavioral analyses, the assessment of spontaneous and induced locomotor activity often plays a crucial role in the research. A number of automated systems able to measure this behavioral parameter have been developed in recent times (Wu et al, 2000;Marchand et al, 2003;Lind et al, 2005;Tort et al, 2006), of which the video-based methods are considered to be the most accurate (Noldus et al, 2001). The majority of video tracking systems were developed and validated for adult animals that usually use rapid running and walking for locomotion.…”

Section: Introductionmentioning

confidence: 99%

Assessment of neonatal rat's activity by the automated registration of the animal entries in the squares of a testing arena

Menshanov

Дыгало

2007

Journal of Neuroscience Methods

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“…However, the most robust systems involve video imaging, and many such systems have been developed (Livesey and Leppard, 1981;Godden and Graham, 1983;Sanberg et al, 1984;Vorhees et al, 1992;Schwarting et al, 1993;Park et al, 1995;Sams-Dodd, 1995;Hoy et al, 1996;Rousseau et al, 2000;Noldus et al, 2001;Spink et al, 2001;Lind et al, 2005;Tort et al, 2006). While the development of sophisticated tech- * Corresponding author.…”

Section: Introductionmentioning

confidence: 99%

Video imaging system for automated shaping and analysis of complex locomotory behavior

Publicover

Hayes

Guerrero³

et al. 2009

Journal of Neuroscience Methods

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A simple webcam-based approach for the measurement of rodent locomotion and other behavioural parameters

Cited by 36 publications

References 28 publications

Calcineurin inhibition blocks within-, but not between-session fear extinction in mice

Calcineurin inhibition blocks within-, but not between-session fear extinction in mice

Assessment of neonatal rat's activity by the automated registration of the animal entries in the squares of a testing arena

Video imaging system for automated shaping and analysis of complex locomotory behavior

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