A Simple Small Size and Low Cost Sensor Based on Surface Plasmon Resonance for Selective Detection of Fe(III)

Abstract

A simple, small size, and low cost sensor based on a Deferoxamine Self Assembled Monolayer (DFO-SAM) and Surface Plasmon Resonance (SPR) transduction, in connection with a Plastic Optical Fiber (POF), has been developed for the selective detection of Fe(III). DFO-SAM sensors based on appropriate electrochemical techniques can be frequently found in the scientific literature. In this work, we present the first example of a DFO-SAM sensor based on SPR in an optical fiber. The SPR sensing platform was realized by removing the cladding of a plastic optical fiber along half the circumference, spin coating a buffer of Microposit S1813 photoresist on the exposed core, and finally sputtering a thin gold film. The hydroxamate siderophore deferoxamine (DFO), having high binding affinity for Fe(III), is then used in its immobilized form, as self-assembled monolayer on the gold layer surface of the POF sensor. The results showed that the DFO-SAM-POF-sensor was able to sense the formation of the Fe(III)/DFO complex in the range of concentrations between 1 μm and 50 μm with a linearity range from 0 to 30 μm of Fe(III). The selectivity of the sensor was also proved by interference tests.

Sensing of Copper(II) by Immobilized Ligands: Comparison of Electrochemical and Surface Plasmon Resonance Transduction

“…A surface plasmon resonance (SPR) sensor is an optical sensor based on the plasmonic phenomenon. In particular, the SPR platform used in the present investigation is based on a D-shaped plastic optical fiber (POF), with a planar surface obtained by erasing the cladding and partially the core, over which a multilayer structure (photoresist buffer layer and thin gold film) was realized as previously described [4][5][6]. On the gold layer of this SPR-POF platform a D,L-penicillamine SAM has been realized.…”

Deferoxamine–paper for iron(III) and vanadium(V) sensing

“…In addition, DFO forms colored complexes with Fe(III) and V(V), which can be used in the colorimetric determination of the two ions. Our research group has already studied how to link DFO to many different solid supports, the most interesting of them being mesoporous silica and the gold surface of an SPR sensor Biesuz et al, 2014;Cennamo et al, 2014).…”

“…In this paper, we focused on the possibility to develop an Fe(III) and V(V) sensor based on the functionalization of common filter paper with DFO to provide a solid phase for free Fe(III) sensing Biesuz et al, 2014;Cennamo et al, 2014).…”

Introduction

“…65 A SPR-based plastic optical fiber sensor was developed for the detection of metal ion, Fe (III) using Deferoxamine-Self Assembled Monolyer (DFO-SAM) over gold coated optical fiber. 66 The formation of Fe (III)/DFO complex changes the resonance wavelength. The SPR-based fiber optic sensors were also developed for the detection of low-density lipoprotein, 67 pH, 68,69 low glucose concentration, 70 phenolic compounds, 71 urea, 72 chromium, 73 triacylglycerides, 74 and heavy metal ions.…”